What is Upstream Bio, Inc.'s price / sales?

Upstream Bio, Inc. (UPB) reported price / sales of 147.4× in Q1 2026.

How has Upstream Bio, Inc.'s price / sales changed year-over-year?

Upstream Bio, Inc.'s price / sales increased by 3.1% year-over-year, from 143× to 147.4×.

What does price / sales mean?

Market capitalization at the quarter end divided by trailing-twelve-month revenue. The price the market pays for each dollar of sales.

Upstream Bio, Inc. UPB Price / sales

Price / sales at other companies

AmgenAMGN

5.1×+0.2×

Regeneron PharmaceuticalsREGN

5.5×+0.6×

Aclaris TherapeuticsACRS

54.3×+45.0×

Shattuck Labs, Inc.STTK

460.2×+450×

AnaptysBio, Inc.ANAB

6.9×+1.8×

Avalo TherapeuticsAVTX

176.3×+173×

Other financials

Income statement

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Revenue$1.0M+82.7%

Operating income-$43.6M-36.2%

Net income-$40.6M-48.8%

EPS (diluted)-$0.75-47.1%

Balance sheet

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Cash & equivalents$96.7M+35.6%

Total debt$1.1M-34.5%

Total equity$304.0M-31.8%

Total assets$318.1M-30.3%

Cash flow

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Operating cash flow-$47.9M-16.2%

CapEx$54.0K-70.8%

Free cash flow-$30.7M-55.0%

Valuation

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Market cap$346.11M-40.9%

Enterprise value$250.5M-51.4%

Profitability

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Operating margin-5,176.5%+1,764pp

Net margin-4,719%+2,752pp

Returns & leverage

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Return on equity-41.8%—

Debt / equity0×0.0×

Current ratio23.1×-24.3×

Where this comes from

Calculated from Upstream Bio, Inc.’s reported figures.

market cap/total revenue=147.4×

Based on the most recent quarter.

The official record: Upstream Bio, Inc.’s 10-Q, filed May 13, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Upstream Bio, Inc.'s price / sales?: Upstream Bio, Inc. (UPB) reported price / sales of 147.4× in Q1 2026.
How has Upstream Bio, Inc.'s price / sales changed year-over-year?: Upstream Bio, Inc.'s price / sales increased by 3.1% year-over-year, from 143× to 147.4×.
What does price / sales mean?: Market capitalization at the quarter end divided by trailing-twelve-month revenue. The price the market pays for each dollar of sales.