What is Upstream Bio, Inc.'s restricted cash?

Upstream Bio, Inc. (UPB) reported restricted cash of $194K in Q1 2026.

How has Upstream Bio, Inc.'s restricted cash changed year-over-year?

Upstream Bio, Inc.'s restricted cash decreased by 0.0% year-over-year, from $194K to $194K.

What does restricted cash mean?

Cash restricted for specific purposes by contractual, regulatory, or legal requirements — not available for general corporate use.

Upstream Bio, Inc. UPB Restricted Cash

Restricted Cash at other companies

Avalo TherapeuticsAVTX

$147K+137%

Theravance BiopharmaTBPH

$836K0.0%

Ethos Technologies, Inc. LIFE

$1.81M-25.8%

Septerna, Inc.SEPN

$905K0.0%

Kymera TherapeuticsKYMR

$5.81M+0.1%

Regeneron PharmaceuticalsREGN

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Other financials

Income statement

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Revenue$1.0M+82.7%

Operating income-$43.6M-36.2%

Net income-$40.6M-48.8%

EPS (diluted)-$0.75-47.1%

Balance sheet

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Cash & equivalents$96.7M+35.6%

Total debt$1.1M-34.5%

Total equity$304.0M-31.8%

Total assets$318.1M-30.3%

Cash flow

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Operating cash flow-$47.9M-16.2%

CapEx$54.0K-70.8%

Free cash flow-$30.7M-55.0%

Valuation

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Market cap$346.11M-40.9%

Enterprise value$250.5M-51.4%

P/S104.2×-151×

Profitability

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Operating margin-5,176.5%+1,764pp

Net margin-4,719%+2,752pp

Returns & leverage

See full

Return on equity-41.8%—

Debt / equity0×0.0×

Current ratio23.1×-24.3×

Where this comes from

Reported directly by Upstream Bio, Inc. in its filing.

Tagged under the XBRL concept us-gaap:RestrictedCashNoncurrent.

The official record: Upstream Bio, Inc.’s 10-Q, filed May 13, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Upstream Bio, Inc.'s restricted cash?: Upstream Bio, Inc. (UPB) reported restricted cash of $194K in Q1 2026.
How has Upstream Bio, Inc.'s restricted cash changed year-over-year?: Upstream Bio, Inc.'s restricted cash decreased by 0.0% year-over-year, from $194K to $194K.
What does restricted cash mean?: Cash restricted for specific purposes by contractual, regulatory, or legal requirements — not available for general corporate use.