What is Upstream Bio, Inc.'s PP&E (net)?

Upstream Bio, Inc. (UPB) reported PP&E (net) of $510K in Q1 2026.

How has Upstream Bio, Inc.'s PP&E (net) changed year-over-year?

Upstream Bio, Inc.'s PP&E (net) decreased by 5.4% year-over-year, from $539K to $510K.

What is the long-term trend for Upstream Bio, Inc.'s PP&E (net)?

Over 2 years (2023 to 2025), Upstream Bio, Inc.'s PP&E (net) has grown at a 87.5% compound annual growth rate (CAGR), from $159K to $559K.

What does PP&E (net) mean?

Total property, plant, and equipment minus accumulated depreciation — the net book value of all tangible long-lived assets.

Upstream Bio, Inc. UPB PP&E (Net)

PP&E (Net) at other companies

AmgenAMGN

$8.22B+23.0%

Aclaris TherapeuticsACRS

$750K-20.4%

Shattuck Labs, Inc.STTK

$5.35M-39.7%

SavaraSVRA

$130K-5.8%

AnaptysBio, Inc.ANAB

$1.28M-26.5%

Theravance BiopharmaTBPH

$5.54M-21.2%

Other financials

Income statement

See full

Revenue$1.0M+82.7%

Operating income-$43.6M-36.2%

Net income-$40.6M-48.8%

EPS (diluted)-$0.75-47.1%

Balance sheet

See full

Cash & equivalents$96.7M+35.6%

Total debt$1.1M-34.5%

Total equity$304.0M-31.8%

Total assets$318.1M-30.3%

Cash flow

See full

Operating cash flow-$47.9M-16.2%

CapEx$54.0K-70.8%

Free cash flow-$30.7M-55.0%

Valuation

See full

Market cap$346.11M-40.9%

Enterprise value$250.5M-51.4%

P/S104.2×-151×

Profitability

See full

Operating margin-5,176.5%+1,764pp

Net margin-4,719%+2,752pp

Returns & leverage

See full

Return on equity-41.8%—

Debt / equity0×0.0×

Current ratio23.1×-24.3×

Where this comes from

Reported directly by Upstream Bio, Inc. in its filing.

Tagged under the XBRL concept us-gaap:PropertyPlantAndEquipmentNet.

The official record: Upstream Bio, Inc.’s 10-Q, filed May 13, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Upstream Bio, Inc.'s PP&E (net)?: Upstream Bio, Inc. (UPB) reported PP&E (net) of $510K in Q1 2026.
How has Upstream Bio, Inc.'s PP&E (net) changed year-over-year?: Upstream Bio, Inc.'s PP&E (net) decreased by 5.4% year-over-year, from $539K to $510K.
What is the long-term trend for Upstream Bio, Inc.'s PP&E (net)?: Over 2 years (2023 to 2025), Upstream Bio, Inc.'s PP&E (net) has grown at a 87.5% compound annual growth rate (CAGR), from $159K to $559K.
What does PP&E (net) mean?: Total property, plant, and equipment minus accumulated depreciation — the net book value of all tangible long-lived assets.