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Vertex Pharmaceuticals VRTX Business Segments

Q1 '26Q4 '25Q3 '25Q2 '25Q1 '25
Product revenues, net by Product
ALYFTREK$424.4M+687%$380.1M$247M$156.8M$53.9M
CASGEVY$42.9M+202%$54.3M+579%$16.9M+745%$30.4M$14.2M
JOURNAVX$29M+2,131%$26.7M$19.6M$12M$1.3M
Other CF product revenues$135.9M-12.5%$237.4M+24.2%$175.8M-5.9%$236.1M+20.2%$155.3M-25.0%
TRIKAFTA/KAFTRIO$2.35B-7.1%$2.57B-5.5%$2.65B+2.7%$2.55B+4.2%$2.54B+2.1%
Cost of Sales by Product
Product revenues, net$160.2M+22.7%$190.8M+25.2%$139.6M+6.1%$140.5M+13.8%$130.6M+20.0%
Royalty$232.6M+0.1%$275.2M+1.5%$275.2M+5.4%$267M+7.5%$232.4M-0.6%
Product revenues, net by Geography
Europe$950M+14.9%$826.6M-14.6%
Other$261M-6.8%$280.1M+27.1%

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Questions, answered.

How does Vertex Pharmaceuticals break its business down?
Vertex Pharmaceuticals (VRTX) reports product revenues, net by product across 5 parts — ALYFTREK, CASGEVY, JOURNAVX, Other CF product revenues and TRIKAFTA/KAFTRIO. Each is extracted from the segment footnotes and tracked over time.
Where does Vertex Pharmaceuticals's segment data come from?
Segment breakdowns are pulled from the segment footnotes in Vertex Pharmaceuticals's SEC filings (the XBRL dimensional tags), so every line ties back to a reported figure. Switch between quarterly, annual, and TTM, or open any segment for its full history.