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Ionis Pharmaceuticals IONS Net gains (losses) on investments

Net gains (losses) on investments at other companies

BridgeBio Pharma logo
BridgeBio PharmaBBIO
-$18.28M-17.5%
Neurocrine Biosciences logo
Neurocrine BiosciencesNBIX
$25.3M+183%
Roivant Sciences logo
Roivant SciencesROIV
$21.59M+201%
Amgen logo
AmgenAMGN
-$143M-111%
Arrowhead Research logo
Arrowhead ResearchARWR
ALN
Alnylam PharmaceuticalsALNY

Other financials

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:GainLossOnInvestments.

The official record: Ionis Pharmaceuticals’s 10-Q, filed April 29, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's net gains (losses) on investments?
Ionis Pharmaceuticals (IONS) reported net gains (losses) on investments of $22.58M in Q1 2026.
How has Ionis Pharmaceuticals's net gains (losses) on investments changed year-over-year?
Ionis Pharmaceuticals's net gains (losses) on investments increased by 1143.6% year-over-year, from -$2.16M to $22.58M.
What does net gains (losses) on investments mean?
The net profit or loss from the company's investment portfolio.
How do you interpret net gains (losses) on investments?
Positive values indicate successful investment performance, while negative values reflect market volatility or poor investment choices.
How does net gains (losses) on investments compare across companies?
Standard metric for companies with significant investment portfolios or strategic equity stakes.