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Ionis Pharmaceuticals IONS Net gains (losses) on investments

Net gains (losses) on investments at other companies

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-$6.72M
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$0+100%
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$329K-75.4%
BridgeBio Pharma logo
BridgeBio PharmaBBIO
-$6.44M+68.1%
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Ligand PharmaceuticalsLGND
-$22K+55.1%

Other financials

Income statement

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Revenue$267.9M-40.7%
Gross profit$265.2M-40.8%
Operating income-$102.3M-173%
Net income-$114.6M-193%
EPS (diluted)-$0.69-199%

Balance sheet

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Cash & equivalents$350.1M+17.7%
Total debt$262.5M-67.0%
Total equity$439.7M-30.4%
Total assets$3.0B+0.3%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$16.1M+30.7%
Free cash flow-$814.6M-399%

Valuation

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Market cap$9.46B+45.4%
Enterprise value$9.37B+33.8%
P/S10.8×+3.9×

Profitability

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Gross margin98.2%-0.7pp
Operating margin-68%-234pp
Net margin-64.7%-299pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-105.5%+336pp
Debt / equity0.6×-0.7×
Current ratio7.9×+5.0×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:GainLossOnInvestments.

The source filing: Ionis Pharmaceuticals’s 10-Q, filed July 29, 2026.

Filed
Jul 29, 2026, 5:05 PM EDT
Fiscal quarter
Q2 FY2026
Calendar quarter
Q2 2026
Accession
0000874015-26-000251
Line itemThree Months Ended / June 30, 2026Three Months Ended / June 30, 2025Six Months Ended / June 30, 2026Six Months Ended / June 30, 2025
Investment income20,23024,68745,71349,354
Interest expense(4,618)(4,114)(9,778)(8,223)
Interest expense related to sale of future royalties(17,506)(18,648)(34,843)(37,470)
Gain (loss) on investments, net(10,182)(18,312)12,401(20,476)
Other income, net987102529569
Income (loss) before income tax benefit (expense)(113,382)123,531(205,692)(23,291)
Income tax benefit (expense)(1,264)20(1,482)(96)
Net income (loss)$$(114,646)$123,551$(207,174)(23,387)

ITEM 1. FINANCIAL STATEMENTS

FAQ

What is Ionis Pharmaceuticals's net gains (losses) on investments?
Ionis Pharmaceuticals (IONS) reported net gains (losses) on investments of -$10.18M in Q2 2026.
How has Ionis Pharmaceuticals's net gains (losses) on investments changed year-over-year?
Ionis Pharmaceuticals's net gains (losses) on investments increased by 44.4% year-over-year, from -$18.31M to -$10.18M.
What does net gains (losses) on investments mean?
Realized and unrealized gains/losses on investments removed from operating cash flow since they're investing-related.

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