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Q1 '26Q4 '25Q3 '25Q2 '25Q1 '25
$246.09M+21.0%$203.33M+29.7%$156.72M-65.3%$452.05M+243%$131.61M-41.9%
$2.98M-62.5%$7.96M+240%$2.34M-43.7%$4.15M+184%$1.46M-61.8%
$243.11M+24.4%$195.37M+26.6%$154.38M-65.5%$447.9M+244%$130.15M-41.6%
98.8%+2.7pp96.1%-2.4pp98.5%-0.6pp99.1%+0.2pp98.9%+0.6pp
$228.9M0.0%$228.9M0.0%$228.9M0.0%$228.9M+1.6%
$150.36M+15.5%$130.19M+34.5%$96.81M+6.8%$90.62M+18.8%$76.25M-13.4%
$363.52M-13.0%$417.79M+31.8%$316.9M+1.5%$312.23M+12.1%$278.47M-17.5%
-$117.42M+45.2%-$214.46M-33.9%-$160.18M-215%$139.82M+195%-$146.86M-32.5%
-47.7%+57.8pp-105.5%-3.3pp-102.2%-133pp30.9%+143pp-111.6%-62.7pp
$5.16M+6.9%$4.83M+14.6%$4.21M+2.4%$4.11M+0.1%$4.11M-2.0%
-$456K+97.2%-$16.29M-4,587%$363K+256%$102K-78.1%$465K+54.0%
-$92.31M+59.5%-$227.92M-77.5%-$128.39M-204%$123.53M+184%-$146.82M-37.2%
$218K-85.3%$1.48M+594%$213K+1,165%-$20K-117%$116K+104%
-$92.53M+59.7%-$229.39M-78.4%-$128.61M-204%$123.55M+184%-$146.94M-40.8%
-37.6%+75.2pp-112.8%-30.8pp-82.1%-109pp27.3%+139pp-111.6%-65.6pp
-$0.56+60.3%-$1.41-76.2%-$0.80-214%$0.70+175%-$0.93-40.9%
-$113.46M+46.1%-$210.56M-33.9%-$157.31M-210%$142.68M+199%-$144.05M-33.2%
-46.1%+57.5pp-103.6%-3.2pp-100.4%-132pp31.6%+141pp-109.5%-61.7pp
-$117.42M+45.2%-$214.46M-33.9%-$160.18M-215%$139.82M+195%-$146.86M-32.5%

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Questions, answered.

What is Ionis Pharmaceuticals's revenue?
Ionis Pharmaceuticals (IONS) generated $1.1B in revenue over the trailing twelve months, up 47.5% year over year.
Is Ionis Pharmaceuticals profitable?
Ionis Pharmaceuticals is not currently profitable: it reported a net loss of $327.0M over the trailing twelve months, a -30.9% net margin.
What are Ionis Pharmaceuticals's profit margins?
Gross margin is 98.4% and operating margin is -33.3%, with a -30.9% net margin.
What is Ionis Pharmaceuticals's earnings per share?
Ionis Pharmaceuticals's diluted EPS over the trailing twelve months is $-2.07.
Where does Ionis Pharmaceuticals's income statement data come from?
Every line is extracted from Ionis Pharmaceuticals's SEC filings (10-K and 10-Q) and tagged in XBRL. Switch between quarterly, annual, and trailing-twelve-month views, or open any line for its full history and peer comparisons.