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TTM Q1 '26TTM Q4 '25TTM Q3 '25TTM Q2 '25TTM Q1 '25
$1.06B+47.5%$943.71M+33.8%$966.96M+20.4%$944.05M+16.1%$717.25M-7.6%
$17.43M+65.5%$15.91M+41.8%$11.78M+12.8%$10.52M-9.1%$10.53M+5.9%
$1.04B+47.3%$927.8M+33.7%$955.17M+20.5%$933.54M+16.4%$706.72M-7.8%
98.4%-0.2pp98.3%-0.1pp98.8%+0.1pp98.9%+0.3pp98.5%-0.2pp
$915.62M+1.6%$912.1M+1.2%$908.57M+0.9%$905.05M+0.6%
$467.98M+60.8%$393.87M+47.3%$351.76M+40.5%$316.59M+22.4%$291.08M+21.4%
$1.41B+18.6%$1.33B+12.3%$1.25B+6.1%$1.21B+2.7%$1.19B+2.1%
-$352.25M+25.4%-$381.69M+19.7%-$278.05M+24.9%-$266.52M+27.0%-$472.43M-21.4%
-33.3%+32.6pp-40.4%+26.9pp-28.8%+17.4pp-28.2%+16.6pp-65.9%-15.8pp
$18.31M+8.0%$17.26M+1.6%$16.63M-4.2%$16.57M-4.8%$16.95M+11.5%
-$16.28M-1,172%-$15.36M-1,254%$1.23M-2.8%$1.01M-71.7%$1.52M-89.3%
-$325.09M+30.0%-$379.6M+17.5%-$258.72M+27.3%-$274.43M+22.1%-$464.16M-27.6%
$1.89M+131%$1.79M+129%-$2.38M-179%-$6.22M-147%-$6.13M-129%
-$326.98M+28.6%-$381.39M+16.0%-$256.34M+28.6%-$268.22M+26.7%-$458.03M-19.0%
-30.9%+33.0pp-40.4%+24.0pp-26.5%+18.2pp-28.4%+16.6pp-63.9%-14.3pp
-$2.07+30.8%-$2.44+19.7%-$1.69+30.7%-$1.84+27.0%-$2.99-12.0%
-$338.65M+26.5%-$369.24M+20.3%-$266.8M+39.4%-$255.17M+32.8%-$460.85M-14.6%
-32%+32.2pp-39.1%+26.6pp-27.6%+27.2pp-27%+19.7pp-64.3%-12.5pp
-$352.25M+25.4%-$381.69M+19.7%-$278.05M+38.6%-$266.52M+32.1%-$472.43M-13.9%

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Questions, answered.

What is Ionis Pharmaceuticals's revenue?
Ionis Pharmaceuticals (IONS) generated $1.1B in revenue over the trailing twelve months, up 47.5% year over year.
Is Ionis Pharmaceuticals profitable?
Ionis Pharmaceuticals is not currently profitable: it reported a net loss of $327.0M over the trailing twelve months, a -30.9% net margin.
What are Ionis Pharmaceuticals's profit margins?
Gross margin is 98.4% and operating margin is -33.3%, with a -30.9% net margin.
What is Ionis Pharmaceuticals's earnings per share?
Ionis Pharmaceuticals's diluted EPS over the trailing twelve months is $-2.07.
Where does Ionis Pharmaceuticals's income statement data come from?
Every line is extracted from Ionis Pharmaceuticals's SEC filings (10-K and 10-Q) and tagged in XBRL. Switch between quarterly, annual, and trailing-twelve-month views, or open any line for its full history and peer comparisons.