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Ionis Pharmaceuticals IONS Effective Income Tax Rate Reconciliation, Percent

Effective Income Tax Rate Reconciliation, Percent at other companies

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CaterpillarCAT
1.8%+0.5pp
RBC Bearings logo
RBC BearingsRBC
0%
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RBC BearingsRBC
$0
SBA Communications logo
SBA CommunicationsSBAC
2.2%
SBA Communications logo
SBA CommunicationsSBAC
1.5%
RBC Bearings logo
RBC BearingsRBC
-$250K

Other financials

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:EffectiveIncomeTaxRateContinuingOperations.

The official record: Ionis Pharmaceuticals’s 10-K, filed February 26, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's effective income tax rate reconciliation, percent?
Ionis Pharmaceuticals (IONS) reported effective income tax rate reconciliation, percent of -$0.01 in Q4 2025.
How has Ionis Pharmaceuticals's effective income tax rate reconciliation, percent changed year-over-year?
Ionis Pharmaceuticals's effective income tax rate reconciliation, percent decreased by 138.5% year-over-year, from $0.01 to -$0.01.
What is the long-term trend for Ionis Pharmaceuticals's effective income tax rate reconciliation, percent?
Over 2 years (2023 to 2025), Ionis Pharmaceuticals's effective income tax rate reconciliation, percent has grown at a -77.3% compound annual growth rate (CAGR), from -$0.17 to -$0.01.
What does effective income tax rate reconciliation, percent mean?
The actual percentage of pre-tax income paid in taxes from ongoing business operations.
How do you interpret effective income tax rate reconciliation, percent?
A rate significantly lower than the statutory rate suggests effective tax planning or the benefit of tax credits, while a higher rate may indicate tax inefficiencies.
How does effective income tax rate reconciliation, percent compare across companies?
A primary metric for comparing tax efficiency across the industry.