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Ionis Pharmaceuticals IONS Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount

Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount at other companies

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-$49.98M-199%

Other financials

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance.

The official record: Ionis Pharmaceuticals’s 10-K, filed February 26, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount?
Ionis Pharmaceuticals (IONS) reported effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount of $23.44M in Q4 2025.
How has Ionis Pharmaceuticals's effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount changed year-over-year?
Ionis Pharmaceuticals's effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount decreased by 38.5% year-over-year, from $38.15M to $23.44M.
What is the long-term trend for Ionis Pharmaceuticals's effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount?
Over 2 years (2023 to 2025), Ionis Pharmaceuticals's effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount has grown at a -26.9% compound annual growth rate (CAGR), from $175.39M to $93.77M.
What does effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount mean?
The change in the reserve set aside for tax assets that may not be usable in the future.
How do you interpret effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount?
An increase suggests management is less confident in realizing future tax benefits, while a decrease suggests improved outlook or utilization.
How does effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount compare across companies?
Common in biotech and high-growth firms with historical losses and significant deferred tax assets.