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Ionis Pharmaceuticals IONS Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount

Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount at other companies

BioCryst Pharmaceuticals logo
BioCryst PharmaceuticalsBCRX
-$13.11M-703%

Other financials

Income statement

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Revenue$267.9M-40.7%
Gross profit$265.2M-40.8%
Operating income-$102.3M-173%
Net income-$114.6M-193%
EPS (diluted)-$0.69-199%

Balance sheet

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Cash & equivalents$350.1M+17.7%
Total debt$262.5M-67.0%
Total equity$439.7M-30.4%
Total assets$3.0B+0.3%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$16.1M+30.7%
Free cash flow-$814.6M-399%

Valuation

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Market cap$9.01B+38.9%
Enterprise value$8.92B+27.7%
P/S10.3×+3.4×

Profitability

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Gross margin98.2%-0.7pp
Operating margin-68%-234pp
Net margin-64.7%-299pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-105.5%+336pp
Debt / equity0.6×-0.7×
Current ratio7.9×+5.0×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance.

The source filing: Ionis Pharmaceuticals’s 10-K, filed February 26, 2026.

Filed
Feb 26, 2026, 4:25 PM EST
Fiscal year
FY2026
Accession
0000874015-26-000115
Foreign tax effects(118)0.0%%
Effect of cross-border tax laws459(0.1)%
Changes in unrecognized tax benefits12,145(3.2)%
Changes in valuation allowances93,773(24.7)%
Tax credits:
Research and development tax credits(17,754)4.7%%
Orphan drug tax credits(30,521)8.0%%
Non-taxable or non-deductible items:

Item 15. Exhibits and Financial Statement Schedules

FAQ

What is Ionis Pharmaceuticals's effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount?
Ionis Pharmaceuticals (IONS) reported effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount of $23.44M in Q4 2025.
How has Ionis Pharmaceuticals's effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount changed year-over-year?
Ionis Pharmaceuticals's effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount decreased by 38.5% year-over-year, from $38.15M to $23.44M.
What is the long-term trend for Ionis Pharmaceuticals's effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount?
Over 2 years (2023 to 2025), Ionis Pharmaceuticals's effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount has grown at a -26.9% compound annual growth rate (CAGR), from $175.39M to $93.77M.
What does effective income tax rate reconciliation, change in deferred tax assets valuation allowance, amount mean?
This represents the adjustment to the valuation allowance for deferred tax assets, reflecting changes in management's assessment of the likelihood that these assets will be realized. A significant change often indicates shifts in future profitability expectations or tax planning strategies.

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