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BioCryst Pharmaceuticals logo
BioCryst PharmaceuticalsBCRX
$1.21M+74.0%

Other financials

Income statement

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Revenue$267.9M-40.7%
Gross profit$265.2M-40.8%
Operating income-$102.3M-173%
Net income-$114.6M-193%
EPS (diluted)-$0.69-199%

Balance sheet

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Cash & equivalents$350.1M+17.7%
Total debt$262.5M-67.0%
Total equity$439.7M-30.4%
Total assets$3.0B+0.3%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$16.1M+30.7%
Free cash flow-$814.6M-399%

Valuation

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Market cap$9.01B+38.9%
Enterprise value$8.92B+27.7%
P/S10.3×+3.4×

Profitability

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Gross margin98.2%-0.7pp
Operating margin-68%-234pp
Net margin-64.7%-299pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-105.5%+336pp
Debt / equity0.6×-0.7×
Current ratio7.9×+5.0×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost.

The source filing: Ionis Pharmaceuticals’s 10-K, filed February 26, 2026.

Filed
Feb 26, 2026, 4:25 PM EST
Fiscal year
FY2026
Accession
0000874015-26-000115
Tax credits:
Research and development tax credits(17,754)4.7%%
Orphan drug tax credits(30,521)8.0%%
Non-taxable or non-deductible items:
Stock-based compensation19,269(5.1)%
Other4,184(1.1)%
Other(288)0.1%%
Effective rate$1,786(0.5)%

Item 15. Exhibits and Financial Statement Schedules

FAQ

What is Ionis Pharmaceuticals's stock-based comp?
Ionis Pharmaceuticals (IONS) reported stock-based comp of $4.82M in Q4 2025.
How has Ionis Pharmaceuticals's stock-based comp changed year-over-year?
Ionis Pharmaceuticals's stock-based comp increased by 79.5% year-over-year, from $2.68M to $4.82M.
What is the long-term trend for Ionis Pharmaceuticals's stock-based comp?
Over 2 years (2023 to 2025), Ionis Pharmaceuticals's stock-based comp has grown at a -0.7% compound annual growth rate (CAGR), from $19.55M to $19.27M.
What does stock-based comp mean?
This represents the tax impact of share-based compensation expenses that are not deductible for income tax purposes. It highlights the difference between accounting expense and tax-deductible expense for equity awards.

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