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Ionis Pharmaceuticals IONS Short-Term Investments

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Other financials

Income statement

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Revenue$267.9M-40.7%
Gross profit$265.2M-40.8%
Operating income-$102.3M-173%
Net income-$114.6M-193%
EPS (diluted)-$0.69-199%

Balance sheet

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Cash & equivalents$350.1M+17.7%
Total debt$262.5M-67.0%
Total equity$439.7M-30.4%
Total assets$3.0B+0.3%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$16.1M+30.7%
Free cash flow-$814.6M-399%

Valuation

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Market cap$9.01B+38.9%
Enterprise value$8.92B+27.7%
P/S10.3×+3.4×

Profitability

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Gross margin98.2%-0.7pp
Operating margin-68%-234pp
Net margin-64.7%-299pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-105.5%+336pp
Debt / equity0.6×-0.7×
Current ratio7.9×+5.0×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:AvailableForSaleSecuritiesDebtSecuritiesCurrent.

The source filing: Ionis Pharmaceuticals’s 10-Q, filed July 29, 2026.

Filed
Jul 29, 2026, 5:05 PM EDT
Fiscal quarter
Q2 FY2026
Calendar quarter
Q2 2026
Accession
0000874015-26-000251
June 30, 2026Amortized / CostGross Unrealized / GainsGross Unrealized / LossesEstimated / Fair Value
Debt securities issued by U.S. government agencies26,43926(20)26,445
Debt securities issued by the U.S. Treasury (1)467,56588(604)467,049
Debt securities issued by states of the U.S. and political subdivisions of the states5,025-(3)5,022
Total debt securities with a maturity of one year or less1,137,717425(1,101)1,137,041
Corporate debt securities349,54587(1,692)347,940
Debt securities issued by U.S. government agencies119,7014(878)118,827
Debt securities issued by the U.S. Treasury181,168-(1,340)179,828
Debt securities issued by states of the U.S. and political subdivisions of the states731-(1)730

ITEM 1. FINANCIAL STATEMENTS

FAQ

What is Ionis Pharmaceuticals's short-term investments?
Ionis Pharmaceuticals (IONS) reported short-term investments of $1.14B in Q2 2026.
How has Ionis Pharmaceuticals's short-term investments changed year-over-year?
Ionis Pharmaceuticals's short-term investments decreased by 14.5% year-over-year, from $1.33B to $1.14B.
What is the long-term trend for Ionis Pharmaceuticals's short-term investments?
Over 5 years (2020 to 2025), Ionis Pharmaceuticals's short-term investments has grown at a 1.1% compound annual growth rate (CAGR), from $1.49B to $1.58B.
What does short-term investments mean?
Marketable securities and other investments with maturities between three months and one year, providing yield above cash while maintaining liquidity.

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