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Ionis Pharmaceuticals IONS Unrealized Gains on Investments

Unrealized Gains on Investments at other companies

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Other financials

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax.

The official record: Ionis Pharmaceuticals’s 10-Q, filed April 29, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's unrealized gains on investments?
Ionis Pharmaceuticals (IONS) reported unrealized gains on investments of $1.11M in Q1 2026.
How has Ionis Pharmaceuticals's unrealized gains on investments changed year-over-year?
Ionis Pharmaceuticals's unrealized gains on investments decreased by 55.8% year-over-year, from $2.5M to $1.11M.
What is the long-term trend for Ionis Pharmaceuticals's unrealized gains on investments?
Over 4 years (2021 to 2025), Ionis Pharmaceuticals's unrealized gains on investments has grown at a 35.2% compound annual growth rate (CAGR), from $1.26M to $4.22M.
What does unrealized gains on investments mean?
The total paper profit on investment securities that have not yet been sold.
How do you interpret unrealized gains on investments?
An increase indicates favorable market conditions for the company's fixed-income holdings, potentially signaling higher portfolio value.
How does unrealized gains on investments compare across companies?
Commonly tracked by peers to monitor the performance of treasury management strategies.