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Ionis Pharmaceuticals IONS Unrealized Losses on Investments (Before Tax)

Unrealized Losses on Investments (Before Tax) at other companies

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Other financials

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax.

The official record: Ionis Pharmaceuticals’s 10-Q, filed April 29, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's unrealized losses on investments (before tax)?
Ionis Pharmaceuticals (IONS) reported unrealized losses on investments (before tax) of $2.73M in Q1 2026.
How has Ionis Pharmaceuticals's unrealized losses on investments (before tax) changed year-over-year?
Ionis Pharmaceuticals's unrealized losses on investments (before tax) increased by 58.3% year-over-year, from $1.73M to $2.73M.
What is the long-term trend for Ionis Pharmaceuticals's unrealized losses on investments (before tax)?
Over 4 years (2021 to 2025), Ionis Pharmaceuticals's unrealized losses on investments (before tax) has grown at a -51.1% compound annual growth rate (CAGR), from $4.31M to $246K.
What does unrealized losses on investments (before tax) mean?
The total paper loss on investment securities that have not yet been sold.
How do you interpret unrealized losses on investments (before tax)?
An increase suggests declining market value of the investment portfolio, often due to rising interest rates or credit concerns.
How does unrealized losses on investments (before tax) compare across companies?
Standard metric for assessing interest rate risk exposure in corporate investment portfolios.