Septerna, Inc. SEPN Ratios & Valuation
| TTM Q1 '26 | TTM Q4 '25 | TTM Q3 '25 | TTM Q2 '25 | TTM Q1 '25 | ||
|---|---|---|---|---|---|---|
| Profitability | ||||||
| Operating margin | -77.1%+71.6pp | -148.6%+201pp | -349.2%+13,722pp | -14,071.1%-4,732pp | -9,339.1%— | |
| Net margin | -49.9%+56.5pp | -106.4%+160pp | -266.8%+11,786pp | -12,053%-3,949pp | -8,104.1%— | |
| EBITDA margin | -74.8%+70.3pp | -145.1%+197pp | -342%+13,515pp | -13,857%— | —— | |
| Liquidity | ||||||
| Current ratio | 4.7×0.0× | 4.7×-1.8× | 6.5×-15.6× | 22.1×— | —— | |
| Quick ratio | 4.7×0.0× | 4.7×-1.8× | 6.5×-15.6× | 22.1×— | —— | |
| Cash ratio | 0.9×-0.5× | 1.4×-2.9× | 4.3×-8.3× | 12.5×— | —— | |
| Leverage | ||||||
| Debt-to-equity | 0.1×— | —— | —— | —— | —— | |
| Debt-to-assets | 0×0.0× | 0×0.0× | 0×0.0× | 0.1×— | —— | |
| Per Share | ||||||
| Book value per share | $8.46-2.0% | $8.63+1.2% | $8.52-0.3% | $8.55+194% | -$9.11-121% | |
| Valuation | ||||||
| Market capitalization | $1.08B-13.6% | $1.25B+48.8% | $838.65M— | —— | —— | |
| Enterprise value | $1.03B-10.5% | $1.15B+112% | $542.77M— | —— | —— | |
| Price / sales | 14.9×-12.2× | 27.2×-10.9× | 38×— | —— | —— | |
| Price / book | 2.9×— | —— | —— | —— | —— | |
| EV / sales | 14.3×-10.8× | 25.1×+0.4× | 24.6×— | —— | —— | |
| Earnings yield | -3.3%+0.6pp | -3.9%+3.1pp | -7%— | —— | —— |
Chart any of these lines over time, or line them up against competitors.
Compare these in charts →Questions, answered.
- Where do Septerna, Inc.'s ratios come from?
- Every ratio is computed from Septerna, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.
