What is Septerna, Inc.'s enterprise value?

Septerna, Inc. (SEPN) reported enterprise value of $1.03B in Q1 2026.

How has Septerna, Inc.'s enterprise value changed year-over-year?

Septerna, Inc.'s enterprise value increased by 1325.4% year-over-year, from $72.3M to $1.03B.

What does enterprise value mean?

Market capitalization plus total debt minus cash, at the quarter end. The cost to acquire the whole business — what an buyer pays for equity and debt, net of the cash they'd inherit.

Septerna, Inc. SEPN Enterprise value

Enterprise value at other companies

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$1.77B+1,855%

Rapport Therapeutics, Inc.RAPP

$1.43B+352%

Nurix Therapeutics, Inc.NRIX

$1.63B+45.1%

Fortrea Holdings Inc.FTRE

$1.85B-0.8%

PrecigenPGEN

$1.46B+234%

Other financials

Income statement

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Revenue$26.5M+12,011%

Operating income-$13.3M+48.7%

Net income-$8.6M+59.8%

EPS (diluted)-$0.19+61.2%

Balance sheet

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Cash & equivalents$71.6M-65.9%

Total debt$23.1M-7.7%

Total equity$378.5M+195%

Total assets$569.7M+31.3%

Cash flow

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Operating cash flow-$25.6M-9.8%

CapEx$832.0K+118%

Free cash flow-$26.5M-11.5%

Valuation

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Market cap$1.65B+319%

P/S22.8×-379×

Profitability

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Operating margin-77.1%-38.4pp

Net margin-49.9%-24.9pp

FCF margin467.9%+243pp

Returns & leverage

See full

Return on equity-12.2%—

Debt / equity0.1×—

Current ratio4.7×-27.5×

Where this comes from

Calculated from Septerna, Inc.’s reported figures.

$1.1Bmarket cap+$23.1Mtotal debt−$71.6Mcash and equivalents=$1.03B

The official record: Septerna, Inc.’s 10-Q, filed May 11, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Septerna, Inc.'s enterprise value?: Septerna, Inc. (SEPN) reported enterprise value of $1.03B in Q1 2026.
How has Septerna, Inc.'s enterprise value changed year-over-year?: Septerna, Inc.'s enterprise value increased by 1325.4% year-over-year, from $72.3M to $1.03B.
What does enterprise value mean?: Market capitalization plus total debt minus cash, at the quarter end. The cost to acquire the whole business — what an buyer pays for equity and debt, net of the cash they'd inherit.