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Septerna, Inc. SEPN Total Revenue

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Other financials

Income statement

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Operating income-$16.8M+41.9%
Net income-$13.0M+47.5%
EPS (diluted)-$0.29+48.2%

Balance sheet

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Cash & equivalents$84.7M-55.3%
Total debt$22.5M-8.2%
Total equity$386.7M+2.4%
Total assets$566.7M+36.5%

Cash flow

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Operating cash flow-$22.2M-9.3%
CapEx$832.0K+118%
Free cash flow-$22.2M-9.0%

Valuation

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Market cap$1.78B+97.7%
Enterprise value$1.71B+184%
P/S18×-22.8×

Profitability

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Operating margin-44%-22.0pp
Net margin-24.5%-12.2pp
FCF margin467.9%+243pp

Returns & leverage

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Return on equity-6.3%—
Debt / equity0.1×0.0×
Current ratio5×-17.1×

Where this comes from

Reported directly by Septerna, Inc. in its filing.

Tagged under the XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax.

The source filing: Septerna, Inc.’s 10-Q, filed August 10, 2026.

Filed
Aug 10, 2026, 4:06 PM EDT
Fiscal quarter
Q2 FY2026
Calendar quarter
Q2 2026
Accession
0001193125-26-342353
Line itemThree Months Ended June 30, 2026Three Months Ended June 30, 2025Six Months Ended June 30, 2026Six Months Ended June 30, 2025
Revenue$26,746$119$53,269$338
Operating expenses:
Research and development35,13222,18864,66741,459
General and administrative8,4506,90918,73813,767
Total operating expenses43,58229,09783,40555,226
Loss from operations(16,836)(28,978)(30,136)(54,888)
Other income, net:
Interest income4,7984,1659,8298,627

Item 1. Condensed Financial Statements.

FAQ

What is Septerna, Inc.'s total revenue?
Septerna, Inc. (SEPN) reported total revenue of $26.75M in Q2 2026.
How has Septerna, Inc.'s total revenue changed year-over-year?
Septerna, Inc.'s total revenue increased by 22375.6% year-over-year, from $119K to $26.75M.
What does total revenue mean?
The aggregate of all revenue from the company's operations — the top line from which all profitability metrics are derived.

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