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Other financials

Income statement

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Revenue$26.5M+12,011%
Operating income-$13.3M+48.7%
Net income-$8.6M+59.8%
EPS (diluted)-$0.19+61.2%

Balance sheet

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Cash & equivalents$71.6M-65.9%
Total debt$23.1M-7.7%
Total equity$378.5M+195%
Total assets$569.7M+31.3%

Cash flow

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Operating cash flow-$25.6M-9.8%
Free cash flow-$26.5M-11.5%

Valuation

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Market cap$1.78B+240%
Enterprise value$1.73B+383%
P/S24.7×-696×

Profitability

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Operating margin-77.1%-38.4pp
Net margin-49.9%-24.9pp
FCF margin467.9%+243pp

Returns & leverage

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Return on equity-12.2%
Debt / equity0.1×
Current ratio4.7×-27.5×

Where this comes from

Reported directly by Septerna, Inc. in its filing.

Tagged under the XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment.

The source filing: Septerna, Inc.’s 10-Q, filed May 11, 2026.

Filed
May 11, 2026, 4:08 PM EDT
Fiscal quarter
Q1 FY2026
Calendar quarter
Q1 2026
Accession
0001193125-26-216759
Line itemThree Months Ended March 31, 2026Three Months Ended March 31, 2025
Other non-current liabilities100
Net cash used in operating activities(25,633)(23,343)
Cash flows from investing activities:
Purchases of property and equipment(832)(382)
Purchases of marketable securities(105,230)(49,715)
Maturities of marketable securities82,24545,223
Net cash used in investing activities(23,817)(4,874)
Cash flows from financing activities:

Item 1. Condensed Financial Statements.

FAQ

What is Septerna, Inc.'s capex?
Septerna, Inc. (SEPN) reported capex of $832K in Q1 2026.
How has Septerna, Inc.'s capex changed year-over-year?
Septerna, Inc.'s capex increased by 117.8% year-over-year, from $382K to $832K.
What does capex mean?
Cash spent on property, plant, and equipment — the primary measure of investment in productive capacity and infrastructure.

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