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Other financials

Income statement

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Revenue$26.5M+12,011%
Operating income-$13.3M+48.7%
EPS (diluted)-$0.19+61.2%

Balance sheet

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Cash & equivalents$71.6M-65.9%
Total debt$23.1M-7.7%
Total equity$378.5M+195%
Total assets$569.7M+31.3%

Cash flow

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Operating cash flow-$25.6M-9.8%
CapEx$832.0K+118%
Free cash flow-$26.5M-11.5%

Valuation

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Market cap$1.78B+240%
Enterprise value$1.73B+383%
P/S24.7×-696×

Profitability

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Operating margin-77.1%-38.4pp
Net margin-49.9%-24.9pp
FCF margin467.9%+243pp

Returns & leverage

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Return on equity-12.2%
Debt / equity0.1×
Current ratio4.7×-27.5×

Where this comes from

Reported directly by Septerna, Inc. in its filing.

Tagged under the XBRL concept us-gaap:NetIncomeLoss.

The source filing: Septerna, Inc.’s 10-Q, filed May 11, 2026.

Filed
May 11, 2026, 4:08 PM EDT
Fiscal quarter
Q1 FY2026
Calendar quarter
Q1 2026
Accession
0001193125-26-216759
Line itemThree Months Ended March 31, 2026Three Months Ended March 31, 2025
Total other income, net5,0004,434
Loss before provision for income taxes(8,300)(21,476)
Provision for income taxes(337)
Net loss attributable to common stockholders$(8,637)$(21,476)
Net loss per share attributable to common stockholders, basic and diluted$(0.19)$(0.49)
Weighted-average shares outstanding, basic and diluted44,758,80043,937,410
Comprehensive loss:
Net loss$(8,637)$(21,476)

Item 1. Condensed Financial Statements.

FAQ

What is Septerna, Inc.'s net income?
Septerna, Inc. (SEPN) reported net income of -$8.64M in Q1 2026.
How has Septerna, Inc.'s net income changed year-over-year?
Septerna, Inc.'s net income increased by 59.8% year-over-year, from -$21.48M to -$8.64M.
What is the long-term trend for Septerna, Inc.'s net income?
Over 2 years (2023 to 2025), Septerna, Inc.'s net income has grown at a 242.0% compound annual growth rate (CAGR), from $4.18M to -$48.88M.
What does net income mean?
The bottom line — total revenue minus all expenses, taxes, and costs. Represents the profit attributable to the company's shareholders after all obligations are met.

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