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Ionis Pharmaceuticals IONS Q1 2025 earnings

Reported April 30, 2025 · Before market open

Revenue$131.6MMiss by $19.0M
EPS-$0.75Beat by $0.36
Revenue estimate$150.6M
EPS estimate-$1.11

Next report

Nov 4, 2026 (in 2 months)
Revenue estimate$181.8M
EPS estimate-$1.22

Financials

Q1 2025

Income statement

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Revenue$131.6M+10.1%
Gross profit$130.1M+10.9%
Operating income-$146.9M+1.8%
Net income-$146.9M-2.9%
EPS (diluted)-$0.93+5.1%

Balance sheet

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Cash & equivalents$264.2M-24.3%
Total debt$159.4M-25.2%
Total equity$475.7M+60.4%
Total assets$2.8B+1.8%

Cash flow

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Operating cash flow-$150.8M-0.6%
CapEx$12.6M+180%
Free cash flow-$163.4M-5.8%

Valuation & ratios

Valuation

as of 03/31/25
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Market cap$4.8B-23.2%
Enterprise value$4.69B-23.2%
P/S6.7×-1.4×

Profitability

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Gross margin98.5%-0.2pp
Operating margin-65.9%+30.2pp
Net margin-63.9%+26.0pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-118.6%+31.0pp
Debt / equity0.3×-0.4×
Current ratio9.7×+2.3×

Segments

By product

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Commercial$76.2M+27.8%
Royalty$64.2M—
Research And Development Revenue$55.4M-7.4%
Spinraza Royalties$48.0M+24.8%
Collaborative Agreement Revenue$45.0M-8.7%

By segment

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Ionis Operations$131.6M+10.1%

FAQ

When did Ionis Pharmaceuticals report Q1 2025 earnings?
Ionis Pharmaceuticals (IONS) reported Q1 2025 earnings on April 30, 2025 before market open.
What were Ionis Pharmaceuticals's Q1 2025 revenue and EPS?
Ionis Pharmaceuticals reported revenue of $131.6M and eps of $-0.75 for Q1 2025.
Did Ionis Pharmaceuticals beat estimates in Q1 2025?
Revenue missed the consensus estimate of $150.6M by $19.0M. EPS beat the consensus estimate of $-1.11 by $0.36.
How did Ionis Pharmaceuticals's Q1 2025 results compare year-over-year?
Compared to the same quarter a year prior, revenue grew 10.6% from $119.0M a year earlier and eps grew 23.5% from $-0.98.
Where can I find Ionis Pharmaceuticals's Q1 2025 SEC filings?
You can read the 8-K earnings release (0001140361-25-016562) and the 10-Q periodic report (0000874015-25-000123) directly on SEC EDGAR. The filing index links above go to sec.gov.