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TTM Q1 '26TTM Q4 '25TTM Q3 '25TTM Q2 '25TTM Q1 '25
$1.06B+12.1%$943.71M-2.4%$966.96M+2.4%$944.05M+31.6%$717.25M+1.7%
$17.43M+9.6%$15.91M+35.0%$11.78M+12.0%$10.52M-0.1%$10.53M-6.1%
$1.04B+12.2%$927.8M-2.9%$955.17M+2.3%$933.54M+32.1%$706.72M+1.8%
98.4%0.0pp98.3%-0.5pp98.8%-0.1pp98.9%+0.4pp98.5%+0.1pp
$915.62M+0.4%$912.1M+0.4%$908.57M+0.4%$905.05M+0.4%
$467.98M+18.8%$393.87M+12.0%$351.76M+11.1%$316.59M+8.8%$291.08M+8.8%
$1.41B+6.4%$1.33B+6.5%$1.25B+2.8%$1.21B+1.8%$1.19B+0.8%
-$352.25M+7.7%-$381.69M-37.3%-$278.05M-4.3%-$266.52M+43.6%-$472.43M+0.6%
-33.3%+7.2pp-40.4%-11.7pp-28.8%-0.5pp-28.2%+37.6pp-65.9%+1.5pp
$18.31M+6.1%$17.26M+3.8%$16.63M+0.3%$16.57M-2.2%$16.95M-0.3%
-$16.28M-6.0%-$15.36M-1,347%$1.23M+21.9%$1.01M-33.4%$1.52M+14.1%
-$325.09M+14.4%-$379.6M-46.7%-$258.72M+5.7%-$274.43M+40.9%-$464.16M-0.9%
$1.89M+5.7%$1.79M+175%-$2.38M+61.7%-$6.22M-1.4%-$6.13M+0.7%
-$326.98M+14.3%-$381.39M-48.8%-$256.34M+4.4%-$268.22M+41.4%-$458.03M-0.9%
-30.9%+9.5pp-40.4%-13.9pp-26.5%+1.9pp-28.4%+35.4pp-63.9%+0.5pp
-$2.07+15.2%-$2.44-44.4%-$1.69+8.2%-$1.84+38.5%-$2.99+1.6%
-$338.65M+8.3%-$369.24M-38.4%-$266.8M-4.6%-$255.17M+44.6%-$460.85M+0.5%
-32%+7.1pp-39.1%-11.5pp-27.6%-0.6pp-27%+37.2pp-64.3%+1.4pp
-$352.25M+7.7%-$381.69M-37.3%-$278.05M-4.3%-$266.52M+43.6%-$472.43M+0.6%

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Questions, answered.

What is Ionis Pharmaceuticals's revenue?
Ionis Pharmaceuticals (IONS) generated $1.1B in revenue over the trailing twelve months, up 47.5% year over year.
Is Ionis Pharmaceuticals profitable?
Ionis Pharmaceuticals is not currently profitable: it reported a net loss of $327.0M over the trailing twelve months, a -30.9% net margin.
What are Ionis Pharmaceuticals's profit margins?
Gross margin is 98.4% and operating margin is -33.3%, with a -30.9% net margin.
What is Ionis Pharmaceuticals's earnings per share?
Ionis Pharmaceuticals's diluted EPS over the trailing twelve months is $-2.07.
Where does Ionis Pharmaceuticals's income statement data come from?
Every line is extracted from Ionis Pharmaceuticals's SEC filings (10-K and 10-Q) and tagged in XBRL. Switch between quarterly, annual, and trailing-twelve-month views, or open any line for its full history and peer comparisons.