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Ionis Pharmaceuticals IONS Foreign operations

Foreign operations at other companies

Belden logo
BeldenBDC
-11.6%+1.4pp
RBC Bearings logo
RBC BearingsRBC
0.3%
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SyscoSYY
-1.1%+0.1pp
McCormick & Company, Incorporated logo
McCormick & Company, IncorporatedMKC
0.7%+0.1pp
CSX logo
CSXCSX
0.1%
Ionis Pharmaceuticals logo
Ionis PharmaceuticalsIONS
0%

Other financials

Income statement

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Revenue$267.9M-40.7%
Gross profit$265.2M-40.8%
Operating income-$102.3M-173%
Net income-$114.6M-193%
EPS (diluted)-$0.69-199%

Balance sheet

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Cash & equivalents$350.1M+17.7%
Total debt$262.5M-67.0%
Total equity$439.7M-30.4%
Total assets$3.0B+0.3%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$16.1M+30.7%
Free cash flow-$814.6M-399%

Valuation

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Market cap$9.01B+38.9%
Enterprise value$8.92B+27.7%
P/S10.3×+3.4×

Profitability

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Gross margin98.2%-0.7pp
Operating margin-68%-234pp
Net margin-64.7%-299pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-105.5%+336pp
Debt / equity0.6×-0.7×
Current ratio7.9×+5.0×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential.

The source filing: Ionis Pharmaceuticals’s 10-K, filed February 26, 2026.

Filed
Feb 26, 2026, 4:25 PM EST
Fiscal year
FY2026
Accession
0000874015-26-000115
Pre-tax loss$(379,601)
Statutory rate(79,716)21.0%%
State and local income tax, net of federal income tax effect (a)353(0.1)%
Foreign tax effects(118)0.0%%
Effect of cross-border tax laws459(0.1)%
Changes in unrecognized tax benefits12,145(3.2)%
Changes in valuation allowances93,773(24.7)%
Tax credits:

Item 15. Exhibits and Financial Statement Schedules

FAQ

What is Ionis Pharmaceuticals's foreign operations?
Ionis Pharmaceuticals (IONS) reported foreign operations of 0% in Q4 2025.
What does foreign operations mean?
This metric measures the percentage point impact of foreign income tax rate differentials on the company's total effective tax rate. It provides a normalized view of how international operations influence the overall tax burden compared to the U.S. statutory rate. It helps investors understand the tax-related benefits or risks of the company's global presence.

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