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Reported May 8, 2025 · Before market open

Revenue-
EPS-$0.74Beat by $0.02
EPS estimate-$0.76

Next report

Aug 4, 2026 (In 6 days)
EPS estimate-$0.71

Financials

Q1 2025

Income statement

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Revenue-
Operating income-$53.6M-12.1%
Net income-$44.8M-2.1%
EPS (diluted)-$0.60+16.7%

Balance sheet

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Cash & equivalents$48.5M-78.7%
Total equity$482.6M+217%
Total assets$569.8M+16.9%

Cash flow

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Operating cash flow-$41.0M-43.6%

Valuation & ratios

Valuation

as of 03/31/25
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Market cap$972.25M-29.1%

Returns & leverage

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Return on equity-65.8%-29.9pp
Current ratio8.1×-3.3×

Segments

By segment

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Reportable Segment-

Versus estimates

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Questions, answered.

When did Spyre Therapeutics, Inc. report Q1 2025 earnings?
Spyre Therapeutics, Inc. (SYRE) reported Q1 2025 earnings on May 8, 2025 before market open.
What were Spyre Therapeutics, Inc.'s Q1 2025 revenue and EPS?
Spyre Therapeutics, Inc. reported revenue of - and eps of $-0.74 for Q1 2025.
Did Spyre Therapeutics, Inc. beat estimates in Q1 2025?
EPS beat the consensus estimate of $-0.76 by $0.02.
How did Spyre Therapeutics, Inc.'s Q1 2025 results compare year-over-year?
Compared to the same quarter a year prior, eps grew 38.3% from $-1.20.
Where can I find Spyre Therapeutics, Inc.'s Q1 2025 SEC filings?
You can read the 10-Q periodic report (0001636282-25-000049) directly on SEC EDGAR. The filing index links above go to sec.gov.