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Q1 '26Q4 '25Q3 '25Q2 '25Q1 '25
$60.41M+45.1%$44.64M-11.6%$45.25M+1.1%$40.15M+23.0%$41.62M+19.2%
$15.23M+27.5%$12.53M+16.4%$11.64M+9.3%$11.79M+2.4%$11.94M-7.0%
$45.64M-14.8%$57.17M-6.7%$56.89M+2.7%$41.94M-5.0%$53.57M+12.1%
$45.64M-14.8%$57.17M-6.7%$56.89M+2.7%$41.94M-5.0%$53.57M+12.1%
-$45.64M+14.8%-$57.17M+6.7%-$56.89M-2.7%-$41.94M+5.0%-$53.57M-12.1%
$7M+7.7%$7.14M+23.6%$5.38M+3.8%$5.87M-0.8%$6.49M+46.5%
-$23.36M-366%$0-100%$45.71M+436%$5.22M-1.7%$8.78M+122%
$30M$0$0$10M$0
-$69.01M-54.1%-$62.53M-11.1%-$11.18M+83.8%-$36.72M+5.5%-$44.79M-2.2%
$0+100%$0-100%$0-100%$0-$15K-147%
-$69.01M-54.1%-$62.53M-11.1%-$11.18M+83.8%-$36.72M+5.5%-$44.77M-2.1%
-$0.74-23.3%-$0.74-208%-$0.15+89.0%-$0.49+43.0%-$0.60+16.7%
-$0.74-23.3%-$0.74+6.3%-$0.15+85.8%-$0.49+16.9%-$0.60+16.7%
78.5M+30.3%64.1M+36.2%60.4M+18.7%60.3M+33.1%60.3M+65.1%
78.5M+30.3%64.1M+36.2%60.4M+18.7%60.3M+33.1%60.3M+65.1%
$30M$0$0$10M$0
$7M+7.7%$7.14M+23.6%$5.38M+3.8%$5.87M-0.8%$6.49M+46.5%
-$30.36M-1,428%$40.33M+314%-$656K-7.5%$2.29M+573%
$60.41M+45.1%$44.64M-11.6%$45.25M+1.1%$40.15M+23.0%$41.62M+19.2%
-$45.64M+14.8%-$57.17M+6.7%-$56.89M-2.7%-$41.94M+5.0%-$53.57M-12.1%
-$57.17M+6.7%-$56.89M-2.7%-$41.94M+5.0%-$53.57M-12.1%
-$45.64M+14.8%-$57.17M+6.7%-$56.89M-2.7%-$41.94M+5.0%-$53.57M-12.1%

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Questions, answered.

Is Spyre Therapeutics, Inc. profitable?
Spyre Therapeutics, Inc. is not currently profitable: it reported a net loss of $179.4M over the trailing twelve months, a -52939.7% net margin.
What is Spyre Therapeutics, Inc.'s earnings per share?
Spyre Therapeutics, Inc.'s diluted EPS over the trailing twelve months is $-2.12.
Where does Spyre Therapeutics, Inc.'s income statement data come from?
Every line is extracted from Spyre Therapeutics, Inc.'s SEC filings (10-K and 10-Q) and tagged in XBRL. Switch between quarterly, annual, and trailing-twelve-month views, or open any line for its full history and peer comparisons.