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TTM Q1 '26TTM Q4 '25TTM Q3 '25TTM Q2 '25TTM Q1 '25
$190.44M+12.4%$171.65M+5.4%$177.5M+21.6%$176.99M+40.6%$169.49M+53.2%
$51.2M+14.1%$47.91M+4.7%$46.15M-6.0%$45.15M-4.0%$44.87M-5.7%
$201.64M-5.9%$209.56M+0.5%$213.64M+10.6%$212.15M+35.8%$214.36M-21.2%
$201.64M-5.9%$209.56M+0.5%$213.64M+10.6%$212.15M+35.8%$214.36M-21.2%
-$201.64M+5.9%-$209.56M-0.5%-$213.64M-10.6%-$212.15M-35.8%-$214.36M+21.0%
$25.39M+8.6%$24.89M+16.8%$23.52M+19.6%$23.33M+48.3%$23.37M+130%
$27.56M+408%$59.7M+9,867%$64.66M+399%$5.34M+118%$5.43M+106%
$40M$10M$10M+443%$10M-39.2%$0
-$179.44M+14.1%-$155.22M+25.4%-$148.98M+30.7%-$206.81M-11.2%-$208.93M+42.6%
$0-100%-$15K-129%-$14K-128%$4K-88.6%$4K-90.5%
-$179.44M+14.1%-$155.2M+25.4%-$148.97M+30.7%-$206.81M-11.2%-$208.93M+42.6%
-$2.12+30.7%-$1.98+37.7%-$1.48-$2.69-$3.06
-$2.12+30.3%-$1.98+37.3%-$2.03-$2.94-$3.04
263.4M+29.4%245.1M+36.3%228M+63.3%218.5M+135%203.5M+295%
263.4M+29.4%245.1M+36.3%228M+63.3%218.5M+135%203.5M+295%
$40M$10M$10M+443%$10M-39.2%$0
$25.39M+8.6%$24.89M+16.8%$23.52M+19.6%$23.33M+48.3%$23.37M+130%
$41.14M+200%-$17.99M+10.7%-$17.94M+8.2%
$190.44M+12.4%$171.65M+5.4%$177.5M+21.6%$176.99M+40.6%$169.49M+53.2%
-$201.64M+5.9%-$209.56M-0.5%-$213.64M-10.6%-$212.15M-35.8%-$214.36M+21.0%
-$209.56M-0.5%-$213.64M-$212.15M-$214.36M
-$201.64M+5.9%-$209.56M-0.5%-$213.64M-10.6%-$212.15M-35.8%-$214.36M+21.0%

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Questions, answered.

Is Spyre Therapeutics, Inc. profitable?
Spyre Therapeutics, Inc. is not currently profitable: it reported a net loss of $179.4M over the trailing twelve months, a -52939.7% net margin.
What is Spyre Therapeutics, Inc.'s earnings per share?
Spyre Therapeutics, Inc.'s diluted EPS over the trailing twelve months is $-2.12.
Where does Spyre Therapeutics, Inc.'s income statement data come from?
Every line is extracted from Spyre Therapeutics, Inc.'s SEC filings (10-K and 10-Q) and tagged in XBRL. Switch between quarterly, annual, and trailing-twelve-month views, or open any line for its full history and peer comparisons.