When did Upstream Bio, Inc. report Q2 2025 earnings?

Upstream Bio, Inc. (UPB) reported Q2 2025 earnings on August 6, 2025 before market open.

What were Upstream Bio, Inc.'s Q2 2025 revenue and EPS?

Upstream Bio, Inc. reported revenue of $937.0K and diluted EPS of $-0.74 for Q2 2025.

Did Upstream Bio, Inc. beat estimates in Q2 2025?

Revenue beat the consensus estimate of $317.0K by $620.0K. EPS missed the consensus estimate of $-0.61 by $0.13.

Where can I find Upstream Bio, Inc.'s Q2 2025 SEC filings?

You can read the 10-Q periodic report (0000950170-25-103534) directly on SEC EDGAR. The filing index links above go to sec.gov.

Upstream Bio, Inc. UPB Q2 2025 earnings

Reported August 6, 2025 · Before market open

Revenue$937.0KBeat by $620.0K Diluted EPS-$0.74Miss by $0.13

Revenue estimate$317.0K

EPS estimate-$0.61

Next report

Aug 5, 2026 (In 3 weeks)

Revenue estimate$431.1K

EPS estimate-$0.78

Financials

Q2 2025

Income statement

See full

Revenue$937.0K+83.7%

Operating income-$44.3M-153%

Net income-$40.0M-172%

EPS (diluted)-$0.74+88.6%

Balance sheet

See full

Cash & equivalents$45.5M-4.0%

Total debt$1.6M—

Total equity$408.7M+379%

Total assets$420.5M—

Cash flow

See full

Operating cash flow-$39.2M-388%

Valuation & ratios

Valuation

as of 06/30/25

See full

Market cap$612.71M—

Enterprise value$568.81M—

P/S225×—

Profitability

See full

Operating margin-4,464.6%+14,312pp

Net margin-3,836.6%-40,870pp

Returns & leverage

See full

Debt / equity0×—

Current ratio38.3×—

Versus estimates

Revenue

Q1 2026$1.0MBeat by $6.3K Q4 2025$668.0KBeat by $84.0K Q3 2025$683.0KBeat by $161.4K

Q2 2025$937.0KBeat by $620.0K

Q1 2025$566.0KBeat by $249.0K Q4 2024$613.0KBeat by $286.8K

Diluted EPS

Q1 2026-$0.75Miss by $0.01 Q4 2025-$0.79Miss by $0.06 Q3 2025-$0.63Beat by $0.15

Q2 2025-$0.74Miss by $0.13

Q1 2025-$0.51Miss by $0.02 Q4 2024-$1.59Miss by $1.03

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Questions, answered.

When did Upstream Bio, Inc. report Q2 2025 earnings?: Upstream Bio, Inc. (UPB) reported Q2 2025 earnings on August 6, 2025 before market open.
What were Upstream Bio, Inc.'s Q2 2025 revenue and EPS?: Upstream Bio, Inc. reported revenue of $937.0K and diluted EPS of $-0.74 for Q2 2025.
Did Upstream Bio, Inc. beat estimates in Q2 2025?: Revenue beat the consensus estimate of $317.0K by $620.0K. EPS missed the consensus estimate of $-0.61 by $0.13.
Where can I find Upstream Bio, Inc.'s Q2 2025 SEC filings?: You can read the 10-Q periodic report (0000950170-25-103534) directly on SEC EDGAR. The filing index links above go to sec.gov.