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Upstream Bio, Inc. UPB Q2 2025 earnings

Reported August 6, 2025 · Before market open

Revenue$937.0KBeat by $620.0K
EPS-$0.74Miss by $0.13
Revenue estimate$317.0K
EPS estimate-$0.61

Next report

Nov 4, 2026 (in 2 months)
Revenue estimate$522.5K
EPS estimate-$0.73

Financials

Q2 2025

Income statement

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Revenue$937.0K+83.7%
Operating income-$44.3M-153%
Net income-$40.0M-172%
EPS (diluted)-$0.74+88.6%

Balance sheet

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Cash & equivalents$45.5M-4.0%
Total debt$1.6M—
Total equity$408.7M+379%
Total assets$420.5M—

Cash flow

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Operating cash flow-$39.2M-388%

Valuation & ratios

Valuation

as of 06/30/25
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Market cap$612.71M—
Enterprise value$568.81M—
P/S225×—

Profitability

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Operating margin-4,464.6%+14,312pp
Net margin-3,836.6%-40,870pp

Returns & leverage

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Debt / equity0×—
Current ratio38.3×—

FAQ

When did Upstream Bio, Inc. report Q2 2025 earnings?
Upstream Bio, Inc. (UPB) reported Q2 2025 earnings on August 6, 2025 before market open.
What were Upstream Bio, Inc.'s Q2 2025 revenue and EPS?
Upstream Bio, Inc. reported revenue of $937.0K and eps of $-0.74 for Q2 2025.
Did Upstream Bio, Inc. beat estimates in Q2 2025?
Revenue beat the consensus estimate of $317.0K by $620.0K. EPS missed the consensus estimate of $-0.61 by $0.13.
Where can I find Upstream Bio, Inc.'s Q2 2025 SEC filings?
You can read the 8-K earnings release (0000950170-25-103528) and the 10-Q periodic report (0000950170-25-103534) directly on SEC EDGAR. The filing index links above go to sec.gov.