What is Prime Medicine's AOCI?

Prime Medicine (PRME) reported AOCI of -$1K in Q1 2026.

How has Prime Medicine's AOCI changed year-over-year?

Prime Medicine's AOCI increased by 93.3% year-over-year, from -$15K to -$1K.

What is the long-term trend for Prime Medicine's AOCI?

Over 4 years (2021 to 2025), Prime Medicine's AOCI has grown at a 32.0% compound annual growth rate (CAGR), from -$27K to $82K.

Accumulated gains and losses bypassing the income statement — unrealized investment gains/losses, currency translation, pension adjustments, and hedge results.

Prime Medicine PRME AOCI

AOCI at other companies

Eli LillyLLY

-$2.83B+24.9%

Vertex PharmaceuticalsVRTX

$24.8M-63.6%

Intellia TherapeuticsNTLA

-$240K-123%

CRISPR TherapeuticsCRSP

-$1.94M-147%

Beam TherapeuticsBEAM

-$1.07M-769%

RegenxbioRGNX

-$870K-14.2%

Other financials

Income statement

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Revenue$838.0K-61.6%

Operating income-$50.7M+3.3%

Net income-$49.1M+5.3%

EPS (diluted)-$0.28+30.0%

Balance sheet

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Cash & equivalents$77.8M-26.6%

Total debt$114.5M-5.5%

Total equity$76.7M-28.3%

Total assets$294.7M-10.2%

Cash flow

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Operating cash flow-$42.7M+12.6%

CapEx$214.0K-91.2%

Free cash flow-$42.9M+16.3%

Valuation

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Market cap$574.36M+111%

Enterprise value$611.08M+113%

P/S124×+6.3×

Profitability

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Operating margin-4,498.1%-1,134pp

Net margin-4,342.4%-1,099pp

FCF margin-3,607.4%—

Returns & leverage

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Return on equity-216.1%+1,519pp

Debt / equity1.5×+0.4×

Current ratio3.8×-1.0×

Where this comes from

Reported directly by Prime Medicine in its filing.

Tagged under the XBRL concept us-gaap:AccumulatedOtherComprehensiveIncomeLossNetOfTax.

The official record: Prime Medicine’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Prime Medicine's AOCI?: Prime Medicine (PRME) reported AOCI of -$1K in Q1 2026.
How has Prime Medicine's AOCI changed year-over-year?: Prime Medicine's AOCI increased by 93.3% year-over-year, from -$15K to -$1K.
What is the long-term trend for Prime Medicine's AOCI?: Over 4 years (2021 to 2025), Prime Medicine's AOCI has grown at a 32.0% compound annual growth rate (CAGR), from -$27K to $82K.
What does AOCI mean?: Accumulated gains and losses bypassing the income statement — unrealized investment gains/losses, currency translation, pension adjustments, and hedge results.