What is Prime Medicine's debt-to-assets?

Prime Medicine (PRME) reported debt-to-assets of 0.4× in Q1 2026.

How has Prime Medicine's debt-to-assets changed year-over-year?

Prime Medicine's debt-to-assets increased by 5.2% year-over-year, from 0.4× to 0.4×.

What is the long-term trend for Prime Medicine's debt-to-assets?

Over 4 years (2021 to 2025), Prime Medicine's debt-to-assets has grown at a 77.1% compound annual growth rate (CAGR), from 0× to 0.3×.

What does debt-to-assets mean?

Total debt divided by total assets at the quarter end. Measures the share of the asset base financed by debt.

Prime Medicine PRME Debt-to-assets

Debt-to-assets at other companies

Eli LillyLLY

0.4×-0.1×

Vertex PharmaceuticalsVRTX

0.1×0.0×

Intellia TherapeuticsNTLA

0.1×0.0×

CRISPR TherapeuticsCRSP

0.3×+0.2×

Beam TherapeuticsBEAM

0.2×+0.1×

RegenxbioRGNX

0.2×0.0×

Other financials

Income statement

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Revenue$838.0K-61.6%

Operating income-$50.7M+3.3%

Net income-$49.1M+5.3%

EPS (diluted)-$0.28+30.0%

Balance sheet

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Cash & equivalents$77.8M-26.6%

Total debt$114.5M-5.5%

Total equity$76.7M-28.3%

Total assets$294.7M-10.2%

Cash flow

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Operating cash flow-$42.7M+12.6%

CapEx$214.0K-91.2%

Free cash flow-$42.9M+16.3%

Valuation

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Market cap$574.36M+111%

Enterprise value$611.08M+113%

P/S124×+6.3×

Profitability

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Operating margin-4,498.1%-1,134pp

Net margin-4,342.4%-1,099pp

FCF margin-3,607.4%—

Returns & leverage

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Return on equity-216.1%+1,519pp

Debt / equity1.5×+0.4×

Current ratio3.8×-1.0×

Where this comes from

Calculated from Prime Medicine’s reported figures.

total debt/total assets=0.4×

Based on the most recent quarter.

The official record: Prime Medicine’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Prime Medicine's debt-to-assets?: Prime Medicine (PRME) reported debt-to-assets of 0.4× in Q1 2026.
How has Prime Medicine's debt-to-assets changed year-over-year?: Prime Medicine's debt-to-assets increased by 5.2% year-over-year, from 0.4× to 0.4×.
What is the long-term trend for Prime Medicine's debt-to-assets?: Over 4 years (2021 to 2025), Prime Medicine's debt-to-assets has grown at a 77.1% compound annual growth rate (CAGR), from 0× to 0.3×.
What does debt-to-assets mean?: Total debt divided by total assets at the quarter end. Measures the share of the asset base financed by debt.