Where do Prime Medicine's ratios come from?

Every ratio is computed from Prime Medicine's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Prime Medicine PRME Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY

Simplified Detailed

	FY'25	FY'24	FY'23	FY'22
Profitability
Operating margin	-4,498.1%+2,289pp	-6,787.4%—	——	——
Net margin	-4,342.4%+2,224pp	-6,566.6%—	——	——
Returns
Return on equity	-146.8%-9.9pp	-136.9%-48.7pp	-88.2%—	——
Efficiency
Asset turnover	0×0.0×	0×—	0×—	0×—
Liquidity
Current ratio	4.8×-0.7×	5.6×+3.0×	2.5×-8.6×	11.1×+6.4×
Leverage
Debt-to-equity	1×+0.7×	0.3×+0.2×	0.1×0.0×	0.1×—
Per Share
Book value per share	$0.81-37.1%	$1.29-11.7%	$1.46-84.3%	$9.33+177%
Valuation
Market capitalization	$574.36M+111%	$382.99M-55.6%	$862.76M-37.4%	$1.38B—
Price / sales	124×—	128.4×—	——	——
Price / book	7.5×+4.9×	2.5×-4.0×	6.5×+2.1×	4.4×—

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Where do Prime Medicine's ratios come from?: Every ratio is computed from Prime Medicine's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.