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Prime Medicine PRME Return on assets

Return on assets at other companies

Eli Lilly logo
Eli LillyLLY
24.5%+10.1pp
Vertex Pharmaceuticals logo
Vertex PharmaceuticalsVRTX
17.6%
Intellia Therapeutics logo
Intellia TherapeuticsNTLA
-45.2%-1.5pp
CRISPR Therapeutics logo
CRISPR TherapeuticsCRSP
-23.2%+14.7pp
Beam Therapeutics logo
Beam TherapeuticsBEAM
-33.3%
Regenxbio logo
RegenxbioRGNX
-69.6%-217pp

Other financials

Income statement

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Revenue$838.0K-61.6%
Operating income-$50.7M+3.3%
Net income-$49.1M+5.3%
EPS (diluted)-$0.28+30.0%

Balance sheet

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Cash & equivalents$77.8M-26.6%
Total debt$114.5M-5.5%
Total equity$76.7M-28.3%
Total assets$294.7M-10.2%

Cash flow

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Operating cash flow-$42.7M+12.6%
CapEx$214.0K-91.2%
Free cash flow-$42.9M+16.3%

Valuation

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Market cap$574.36M+111%
Enterprise value$611.08M+113%
P/S124×+6.3×

Profitability

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Operating margin-4,498.1%-1,134pp
Net margin-4,342.4%-1,099pp
FCF margin-3,607.4%

Returns & leverage

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Return on equity-216.1%+1,519pp
Debt / equity1.5×+0.4×
Current ratio3.8×-1.0×

Where this comes from

Calculated from Prime Medicine’s reported figures.

Based on trailing twelve months.

The official record: Prime Medicine’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Prime Medicine's return on assets?
Prime Medicine (PRME) reported return on assets of -63.7% in Q1 2026.
How has Prime Medicine's return on assets changed year-over-year?
Prime Medicine's return on assets decreased by 0.8% year-over-year, from -63.2% to -63.7%.
What is the long-term trend for Prime Medicine's return on assets?
Over 3 years (2022 to 2025), Prime Medicine's return on assets has grown at a 19.5% compound annual growth rate (CAGR), from -36.8% to -62.8%.
What does return on assets mean?
Trailing-twelve-month net income divided by average total assets. Measures how efficiently the asset base generates profit, independent of how those assets are financed. Computed as net income over average total assets — note this is OpenCapital's standard definition and may differ from data vendors that use alternative numerators.