Where do Spyre Therapeutics, Inc.'s ratios come from?

Every ratio is computed from Spyre Therapeutics, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

	FY'25	FY'24	FY'23	FY'22
Returns
Return on equity	-25.2%+34.1pp	-59.3%+230pp	-289.2%-164pp	-124.9%-66.1pp
Return on assets	-22.4%+21.4pp	-43.8%+120pp	-164.1%-71.5pp	-92.6%-44.1pp
Efficiency
Asset turnover	0×—	0×0.0×	0×0.0×	0×-0.1×
Liquidity
Current ratio	13.3×+2.0×	11.3×+0.6×	10.7×+6.4×	4.2×-0.7×
Quick ratio	13.3×+2.0×	11.3×+0.6×	10.7×+6.4×	4.2×-0.7×
Cash ratio	1.5×-0.2×	1.7×-4.3×	5.9×+3.4×	2.5×+1.6×
Per Share
Book value per share	$11.17+1.4%	$11.01-58.7%	$26.68+78.8%	$14.92-53.3%
Valuation
Market capitalization	$2.54B+82.6%	$1.39B+79.6%	$775.17M+2,536%	$29.41M-90.6%
Price / book	3.6×+0.9×	2.7×-1.5×	4.2×+3.6×	0.6×-3.1×
Earnings yield	-6.1%+8.8pp	-14.9%+28.8pp	-43.7%+241pp	-285%-264pp

Chart any of these lines over time, or line them up against competitors.

Compare these in charts →

Questions, answered.

Where do Spyre Therapeutics, Inc.'s ratios come from?: Every ratio is computed from Spyre Therapeutics, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.