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Earnings yield at other companies

Bristol-Myers Squibb logo
Bristol-Myers SquibbBMY
5.9%+1.6pp
Eli Lilly logo
Eli LillyLLY
3.1%+1.6pp
Pfizer logo
PfizerPFE
6.8%
Johnson & Johnson logo
Johnson & JohnsonJNJ
3.6%-1.9pp
Merck & Co. logo
Merck & Co.MRK
3%-4.7pp
AbbVie logo
AbbVieABBV
0.9%-0.2pp

Other financials

Income statement

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Revenue-
Operating income-$45.6M+14.8%
Net income-$69.0M-54.1%
EPS (diluted)-$0.74-23.3%

Balance sheet

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Cash & equivalents$97.2M+100%
Total debt$4.3M-9.6%
Total equity$670.8M+39.0%
Total assets$764.0M+34.1%

Cash flow

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Operating cash flow-$57.4M-40.0%
CapEx-
Free cash flow-$39.4M-26.8%

Valuation

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Market cap$7.67B+307%

Profitability

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Operating margin-39,428.9%-49,795pp
Net margin-52,939.7%-61,871pp
FCF margin-3,442.8%-3,807pp

Returns & leverage

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Return on equity-31.1%-10.7pp
Debt / equity0.1×+0.1×
Current ratio+0.9×

Where this comes from

Calculated from Spyre Therapeutics, Inc.’s reported figures.

Based on trailing twelve months.

The official record: Spyre Therapeutics, Inc.’s 10-Q, filed May 5, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Spyre Therapeutics, Inc.'s earnings yield?
Spyre Therapeutics, Inc. (SYRE) reported earnings yield of -4.5% in Q1 2026.
How has Spyre Therapeutics, Inc.'s earnings yield changed year-over-year?
Spyre Therapeutics, Inc.'s earnings yield increased by 78.9% year-over-year, from -21.5% to -4.5%.
What is the long-term trend for Spyre Therapeutics, Inc.'s earnings yield?
Over 5 years (2020 to 2025), Spyre Therapeutics, Inc.'s earnings yield has grown at a -20.5% compound annual growth rate (CAGR), from -19.3% to -6.1%.
What does earnings yield mean?
The company's annual profit as a percentage of its market price — the flip side of the P/E.
How do you interpret earnings yield?
Higher means more earnings per dollar invested. Easy to compare directly against bond yields to judge the relative attractiveness of equity.
How does earnings yield compare across companies?
Comparable across profitable companies and against fixed-income yields; undefined when earnings are negative.