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Upstream Bio, Inc. UPB Invested capital

Discontinued — last reported Q2 '26

Invested capital at other companies

Oneok logo
OneokOKE
8.6%-0.2pp
Rithm Capital logo
Rithm CapitalRITM
3.2%0.0pp
Citigroup logo
CitigroupC
32.6%+2.0pp
Morgan Stanley logo
Morgan StanleyMS
16.9%+0.4pp
Wells Fargo & Company logo
Wells Fargo & CompanyWFC
20.5%-0.7pp
American Express logo
American ExpressAXP
49.1%-10.0pp

Other financials

Income statement

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Revenue$773.0K-17.5%
Operating income-$42.4M+4.5%
Net income-$39.7M+0.7%
EPS (diluted)-$0.73+1.4%

Balance sheet

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Cash & equivalents$79.4M+74.7%
Total debt$954.0K-38.9%
Total equity$271.0M-33.7%
Total assets$281.2M-33.1%

Cash flow

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Operating cash flow-$35.6M+9.2%
CapEx$54.0K-70.8%
Free cash flow-$30.7M-55.0%

Valuation

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Market cap$404.88M-54.7%
Enterprise value$326.44M-61.6%
P/S128.2×-200×

Profitability

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Operating margin-5,382.6%+1,393pp
Net margin-4,955.7%+2,041pp

Returns & leverage

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Return on equity-46%
Debt / equity0.0×
Current ratio28×-10.3×

Where this comes from

Calculated from Upstream Bio, Inc.’s reported figures.

The source filing: Upstream Bio, Inc.’s 10-Q, filed August 11, 2026. Open the filing →

Filed
Aug 11, 2026, 7:10 AM EDT
Fiscal quarter
Q2 FY2026
Calendar quarter
Q2 2026
Accession
0001193125-26-343417

FAQ

What is Upstream Bio, Inc.'s invested capital?
Upstream Bio, Inc. (UPB) reported invested capital of $192.51M in Q2 2026.
How has Upstream Bio, Inc.'s invested capital changed year-over-year?
Upstream Bio, Inc.'s invested capital decreased by 47.2% year-over-year, from $364.85M to $192.51M.
What is the long-term trend for Upstream Bio, Inc.'s invested capital?
Over 2 years (2023 to 2025), Upstream Bio, Inc.'s invested capital has grown at a 26.8% compound annual growth rate (CAGR), from -$148.91M to $239.46M.
What does invested capital mean?
Total debt plus shareholders' equity minus cash, at the quarter end. The capital actually put to work in the operating business — the denominator of return on invested capital (ROIC).

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