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Upstream Bio, Inc. UPB Invested capital

Discontinued — last reported Q1 '26

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Other financials

Income statement

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Revenue$1.0M+82.7%
Operating income-$43.6M-36.2%
Net income-$40.6M-48.8%
EPS (diluted)-$0.75-47.1%

Balance sheet

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Cash & equivalents$96.7M+35.6%
Total debt$1.1M-34.5%
Total equity$304.0M-31.8%
Total assets$318.1M-30.3%

Cash flow

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Operating cash flow-$47.9M-16.2%
CapEx$54.0K-70.8%
Free cash flow-$30.7M-55.0%

Valuation

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Market cap$346.11M-40.9%
Enterprise value$250.5M-51.4%
P/S104.2×-151×

Profitability

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Operating margin-5,176.5%+1,764pp
Net margin-4,719%+2,752pp

Returns & leverage

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Return on equity-41.8%—
Debt / equity0×0.0×
Current ratio23.1×-24.3×

Where this comes from

Calculated from Upstream Bio, Inc.’s reported figures.

$1.1Mtotal debt+$304.0Mtotal stockholders equity−$96.7Mcash and equivalents=$208.39M

The official record: Upstream Bio, Inc.’s 10-Q, filed May 13, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Upstream Bio, Inc.'s invested capital?
Upstream Bio, Inc. (UPB) reported invested capital of $208.39M in Q1 2026.
How has Upstream Bio, Inc.'s invested capital changed year-over-year?
Upstream Bio, Inc.'s invested capital decreased by 44.6% year-over-year, from $376M to $208.39M.
What is the long-term trend for Upstream Bio, Inc.'s invested capital?
Over 2 years (2023 to 2025), Upstream Bio, Inc.'s invested capital has grown at a 26.8% compound annual growth rate (CAGR), from -$148.91M to $239.46M.
What does invested capital mean?
Total debt plus shareholders' equity minus cash, at the quarter end. The capital actually put to work in the operating business — the denominator of return on invested capital (ROIC).