What is Upstream Bio, Inc.'s investing cash flow?

Upstream Bio, Inc. (UPB) reported investing cash flow of $42.4M in Q1 2026.

How has Upstream Bio, Inc.'s investing cash flow changed year-over-year?

Upstream Bio, Inc.'s investing cash flow increased by 119.9% year-over-year, from -$213.38M to $42.4M.

What does investing cash flow mean?

Total net cash provided by or used in investing activities — capex, acquisitions, investment purchases/sales, and other investing items.

Upstream Bio, Inc. UPB Investing Cash Flow

Investing Cash Flow at other companies

AmgenAMGN

-$716M-60.2%

Regeneron PharmaceuticalsREGN

-$428.9M-166%

Aclaris TherapeuticsACRS

-$30.93M-262%

Shattuck Labs, Inc.STTK

$23.85M+52.9%

SavaraSVRA

$38.78M+32.2%

AnaptysBio, Inc.ANAB

$34.98M+136%

Other financials

Income statement

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Revenue$1.0M+82.7%

Operating income-$43.6M-36.2%

Net income-$40.6M-48.8%

EPS (diluted)-$0.75-47.1%

Balance sheet

See full

Cash & equivalents$96.7M+35.6%

Total debt$1.1M-34.5%

Total equity$304.0M-31.8%

Total assets$318.1M-30.3%

Cash flow

See full

Operating cash flow-$47.9M-16.2%

CapEx$54.0K-70.8%

Free cash flow-$30.7M-55.0%

Valuation

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Market cap$346.11M-40.9%

Enterprise value$250.5M-51.4%

P/S104.2×-151×

Profitability

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Operating margin-5,176.5%+1,764pp

Net margin-4,719%+2,752pp

Returns & leverage

See full

Return on equity-41.8%—

Debt / equity0×0.0×

Current ratio23.1×-24.3×

Where this comes from

Reported directly by Upstream Bio, Inc. in its filing.

Tagged under the XBRL concept us-gaap:NetCashProvidedByUsedInInvestingActivities.

The official record: Upstream Bio, Inc.’s 10-Q, filed May 13, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Upstream Bio, Inc.'s investing cash flow?: Upstream Bio, Inc. (UPB) reported investing cash flow of $42.4M in Q1 2026.
How has Upstream Bio, Inc.'s investing cash flow changed year-over-year?: Upstream Bio, Inc.'s investing cash flow increased by 119.9% year-over-year, from -$213.38M to $42.4M.
What does investing cash flow mean?: Total net cash provided by or used in investing activities — capex, acquisitions, investment purchases/sales, and other investing items.