Upstream Bio, Inc. UPB Ratios & Valuation
| TTM Q1 '26 | TTM Q4 '25 | TTM Q3 '25 | TTM Q2 '25 | TTM Q1 '25 | ||
|---|---|---|---|---|---|---|
| Profitability | ||||||
| Operating margin | -5,176.5%-1,049pp | -5,618.8%— | -5,020.1%— | -4,464.6%— | -4,127.4%— | |
| Net margin | -4,719%-1,270pp | -5,026%— | -4,366.8%— | -3,836.6%— | -3,448.7%— | |
| Liquidity | ||||||
| Current ratio | 23.1×— | 26.2×— | 32.7×— | 38.3×— | —— | |
| Leverage | ||||||
| Debt-to-equity | 0×— | 0×— | 0×— | —— | —— | |
| Per Share | ||||||
| Book value per share | $5.60-32.7% | $6.31-81.6% | $7.02+113% | $7.60+116% | $8.31— | |
| Valuation | ||||||
| Market capitalization | $346.11M-40.9% | $1.47B— | $1.01B— | —— | —— | |
| Price / sales | 104.2×-151× | 514.1×— | 362.3×— | —— | —— | |
| Price / book | 1.1×-0.2× | 4.3×— | 2.7×— | —— | —— |
Chart any of these lines over time, or line them up against competitors.
Compare these in charts →Questions, answered.
- Where do Upstream Bio, Inc.'s ratios come from?
- Every ratio is computed from Upstream Bio, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.
