What is Upstream Bio, Inc.'s shares (diluted)?

Upstream Bio, Inc. (UPB) reported shares (diluted) of 54.3M in Q1 2026.

How has Upstream Bio, Inc.'s shares (diluted) changed year-over-year?

Upstream Bio, Inc.'s shares (diluted) increased by 1.3% year-over-year, from 53.6M to 54.3M.

What does shares (diluted) mean?

The weighted-average shares outstanding plus all potentially dilutive shares from stock options, RSUs, convertible securities, and warrants, using the treasury stock method.

Upstream Bio, Inc. UPB Shares (Diluted)

Shares (Diluted) at other companies

AmgenAMGN

544M+0.6%

Regeneron PharmaceuticalsREGN

107.7M-3.1%

Aclaris TherapeuticsACRS

128.8M+5.2%

Shattuck Labs, Inc.STTK

112.2M+120%

SavaraSVRA

253.3M+17.2%

AnaptysBio, Inc.ANAB

28.7M-6.4%

Other financials

Income statement

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Revenue$1.0M+82.7%

Operating income-$43.6M-36.2%

Net income-$40.6M-48.8%

EPS (diluted)-$0.75-47.1%

Balance sheet

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Cash & equivalents$96.7M+35.6%

Total debt$1.1M-34.5%

Total equity$304.0M-31.8%

Total assets$318.1M-30.3%

Cash flow

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Operating cash flow-$47.9M-16.2%

CapEx$54.0K-70.8%

Free cash flow-$30.7M-55.0%

Valuation

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Market cap$346.11M-40.9%

Enterprise value$250.5M-51.4%

P/S104.2×-151×

Profitability

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Operating margin-5,176.5%+1,764pp

Net margin-4,719%+2,752pp

Returns & leverage

See full

Return on equity-41.8%—

Debt / equity0×0.0×

Current ratio23.1×-24.3×

Where this comes from

Reported directly by Upstream Bio, Inc. in its filing.

Tagged under the XBRL concept us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding.

The official record: Upstream Bio, Inc.’s 10-Q, filed May 13, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Upstream Bio, Inc.'s shares (diluted)?: Upstream Bio, Inc. (UPB) reported shares (diluted) of 54.3M in Q1 2026.
How has Upstream Bio, Inc.'s shares (diluted) changed year-over-year?: Upstream Bio, Inc.'s shares (diluted) increased by 1.3% year-over-year, from 53.6M to 54.3M.
What does shares (diluted) mean?: The weighted-average shares outstanding plus all potentially dilutive shares from stock options, RSUs, convertible securities, and warrants, using the treasury stock method.