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Ionis Pharmaceuticals IONS AFS and Trading Securities - Unrealized Loss Position (<12 Months) Accumulated Loss

AFS and Trading Securities - Unrealized Loss Position (<12 Months) Accumulated Loss at other companies

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-$123.4M-168%
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$113M+304%
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$8.42M
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$4.06M
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$9.15M-81.8%
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$812M-29.1%

Other financials

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsNumberOfPositions.

The official record: Ionis Pharmaceuticals’s 10-Q, filed April 29, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's AFS and trading securities - unrealized loss position (<12 months) accumulated loss?
Ionis Pharmaceuticals (IONS) reported AFS and trading securities - unrealized loss position (<12 months) accumulated loss of 368 in Q1 2026.
How has Ionis Pharmaceuticals's AFS and trading securities - unrealized loss position (<12 months) accumulated loss changed year-over-year?
Ionis Pharmaceuticals's AFS and trading securities - unrealized loss position (<12 months) accumulated loss increased by 17.9% year-over-year, from 312 to 368.
What does AFS and trading securities - unrealized loss position (<12 months) accumulated loss mean?
The total temporary paper losses on short-term investment holdings held for less than a year.
How do you interpret AFS and trading securities - unrealized loss position (<12 months) accumulated loss?
An increase suggests rising interest rates or market volatility affecting the company's short-term investment portfolio.
How does AFS and trading securities - unrealized loss position (<12 months) accumulated loss compare across companies?
Commonly reported by biotech firms with significant cash reserves invested in fixed-income securities.