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Ionis Pharmaceuticals IONS Interest coverage

Interest coverage at other companies

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-2.4×+0.9×
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3.4×+2.9×
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-7.1×-0.8×
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Neurocrine BiosciencesNBIX
101×+77.4×
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Roivant SciencesROIV
122.5×+104×
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Royalty PharmaRPRX
4.7×-3.0×

Other financials

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Calculated from Ionis Pharmaceuticals’s reported figures.

Based on trailing twelve months.

The official record: Ionis Pharmaceuticals’s 10-Q, filed April 29, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's interest coverage?
Ionis Pharmaceuticals (IONS) reported interest coverage of -19.2× in Q1 2026.
How has Ionis Pharmaceuticals's interest coverage changed year-over-year?
Ionis Pharmaceuticals's interest coverage increased by 31.0% year-over-year, from -27.9× to -19.2×.
What is the long-term trend for Ionis Pharmaceuticals's interest coverage?
Over 5 years (2020 to 2025), Ionis Pharmaceuticals's interest coverage has grown at a 4.1% compound annual growth rate (CAGR), from -18.1× to -22.1×.
What does interest coverage mean?
How many times the company's operating profit covers its interest bill.
How do you interpret interest coverage?
Higher is safer; below ~2× is a warning that earnings provide little cushion against the debt burden. Debt-free companies have no interest expense and the ratio is left blank.
How does interest coverage compare across companies?
Comparable across leveraged non-financials; less relevant for net-cash companies with negligible interest.