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Ionis Pharmaceuticals IONS Accrued Clinical Expenses

Accrued Clinical Expenses at other companies

Exelixis logo
ExelixisEXEL
$64.8M+12.4%
BridgeBio Pharma logo
BridgeBio PharmaBBIO
$54.43M+61.8%
Polaryx Therapeutics, Inc.
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Polaryx Therapeutics, Inc. PLYX
$86K
Revolution Medicines, Inc. logo
Revolution Medicines, Inc.RVMD
$192.45M+96.2%
BridgeBio Pharma logo
BridgeBio PharmaBBIO
$12.99M+2,124%
Incyte logo
IncyteINCY
$1.4M

Other financials

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept ions:AccruedClinicalExpenses.

The official record: Ionis Pharmaceuticals’s 10-Q, filed April 29, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's accrued clinical expenses?
Ionis Pharmaceuticals (IONS) reported accrued clinical expenses of $53.33M in Q1 2026.
How has Ionis Pharmaceuticals's accrued clinical expenses changed year-over-year?
Ionis Pharmaceuticals's accrued clinical expenses decreased by 21.1% year-over-year, from $67.61M to $53.33M.
What does accrued clinical expenses mean?
Unpaid costs for clinical trials that have already been conducted.
How do you interpret accrued clinical expenses?
An increase typically signals active, ongoing clinical trial enrollment and research activity, while a decrease may indicate the completion of major study phases.
How does accrued clinical expenses compare across companies?
Standard liability for clinical-stage biotech companies, reflecting the intensity of the R&D pipeline.