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Other financials

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:CurrentForeignTaxExpenseBenefit.

The official record: Ionis Pharmaceuticals’s 10-K, filed February 26, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's foreign?
Ionis Pharmaceuticals (IONS) reported foreign of $55.25K in Q4 2025.
How has Ionis Pharmaceuticals's foreign changed year-over-year?
Ionis Pharmaceuticals's foreign increased by 30.8% year-over-year, from $42.25K to $55.25K.
What is the long-term trend for Ionis Pharmaceuticals's foreign?
Over 2 years (2023 to 2025), Ionis Pharmaceuticals's foreign has grown at a 22.6% compound annual growth rate (CAGR), from $147K to $221K.
What does foreign mean?
The current period's income tax expense owed to foreign governments.
How do you interpret foreign?
Changes indicate shifts in international profitability or changes in foreign tax regulations.
How does foreign compare across companies?
Standard disclosure for multinational entities with international tax footprints.