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Ionis Pharmaceuticals IONS Effective Income Tax Rate Reconciliation Orphan Drug Tax Credits Amount

Effective Income Tax Rate Reconciliation Orphan Drug Tax Credits Amount at other companies

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Other financials

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept ions:EffectiveIncomeTaxRateReconciliationOrphanDrugTaxCreditsAmount.

The official record: Ionis Pharmaceuticals’s 10-K, filed February 26, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's effective income tax rate reconciliation orphan drug tax credits amount?
Ionis Pharmaceuticals (IONS) reported effective income tax rate reconciliation orphan drug tax credits amount of -$7.63M in Q4 2025.
What does effective income tax rate reconciliation orphan drug tax credits amount mean?
The total tax savings realized from orphan drug development incentives.
How do you interpret effective income tax rate reconciliation orphan drug tax credits amount?
Higher values indicate successful development of rare disease therapies and effective capture of specialized tax incentives.
How does effective income tax rate reconciliation orphan drug tax credits amount compare across companies?
Specific to biopharmaceutical companies focusing on rare disease pipelines.