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Ionis Pharmaceuticals IONS Changes in unrecognized tax benefits

Changes in unrecognized tax benefits at other companies

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Jazz PharmaceuticalsJAZZ
0.9%—

Other financials

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:EffectiveIncomeTaxRateReconciliationTaxContingencies.

The official record: Ionis Pharmaceuticals’s 10-K, filed February 26, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's changes in unrecognized tax benefits?
Ionis Pharmaceuticals (IONS) reported changes in unrecognized tax benefits of -3.2% in Q4 2025.
What does changes in unrecognized tax benefits mean?
The percentage impact of uncertain tax positions on the effective tax rate.
How do you interpret changes in unrecognized tax benefits?
Higher values indicate that tax uncertainty is significantly influencing the reported tax rate.
How does changes in unrecognized tax benefits compare across companies?
Standard disclosure in effective tax rate reconciliation tables.