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Ionis Pharmaceuticals IONS Effective Income Tax Rate Reconciliation Tax Credits Research

Effective Income Tax Rate Reconciliation Tax Credits Research at other companies

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-5.6%

Other financials

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:EffectiveIncomeTaxRateReconciliationTaxCreditsResearch.

The official record: Ionis Pharmaceuticals’s 10-K, filed February 26, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's effective income tax rate reconciliation tax credits research?
Ionis Pharmaceuticals (IONS) reported effective income tax rate reconciliation tax credits research of -4.7% in Q4 2025.
What does effective income tax rate reconciliation tax credits research mean?
The percentage reduction in the effective tax rate attributed to research and development tax credits.
How do you interpret effective income tax rate reconciliation tax credits research?
An increase indicates that R&D tax credits are becoming a more significant factor in reducing the company's effective tax rate.
How does effective income tax rate reconciliation tax credits research compare across companies?
Standard metric for comparing the tax-efficiency of R&D-heavy companies across the industry.