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Ionis Pharmaceuticals IONS Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount

Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount at other companies

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-$1.37M

Other financials

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:IncomeTaxReconciliationStateAndLocalIncomeTaxes.

The official record: Ionis Pharmaceuticals’s 10-K, filed February 26, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's effective income tax rate reconciliation, state and local income taxes, amount?
Ionis Pharmaceuticals (IONS) reported effective income tax rate reconciliation, state and local income taxes, amount of $88.25K in Q4 2025.
How has Ionis Pharmaceuticals's effective income tax rate reconciliation, state and local income taxes, amount changed year-over-year?
Ionis Pharmaceuticals's effective income tax rate reconciliation, state and local income taxes, amount increased by 103.0% year-over-year, from -$2.97M to $88.25K.
What is the long-term trend for Ionis Pharmaceuticals's effective income tax rate reconciliation, state and local income taxes, amount?
Over 2 years (2023 to 2025), Ionis Pharmaceuticals's effective income tax rate reconciliation, state and local income taxes, amount has grown at a -87.5% compound annual growth rate (CAGR), from -$22.6M to $353K.
What does effective income tax rate reconciliation, state and local income taxes, amount mean?
The tax expense or benefit attributable to state and local jurisdictions.
How do you interpret effective income tax rate reconciliation, state and local income taxes, amount?
An increase suggests higher tax burdens in state jurisdictions or changes in state-level tax legislation.
How does effective income tax rate reconciliation, state and local income taxes, amount compare across companies?
Commonly disclosed in tax reconciliation notes for companies with multi-state operations.