What is Ionis Pharmaceuticals's revenue?

Ionis Pharmaceuticals (IONS) reported revenue of $203.33M in Q4 2025.

What does revenue mean?

The total amount of money brought in by the company from its business activities.

How do you interpret revenue?

An increase indicates successful commercialization, pipeline execution, or growth in partnership-based revenue streams.

How does revenue compare across companies?

The most fundamental metric for comparing the scale and growth trajectory of companies within the same industry.

Ionis Pharmaceuticals IONS Revenue

Revenue at other companies

Eversource EnergyES

$1.77B-2.7%

NRG EnergyNRG

$10.26B+19.5%

WEC Energy GroupWEC

$48.6M+48.6%

AmerenAEE

$1.66B+2.4%

FirstEnergyFE

$3.24B+5.3%

EVR

EvergyEVRG

$893.4M—

Other financials

Income statement

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Revenue$246.1M+87.0%

Gross profit$243.1M+86.8%

Operating income-$117.4M+20.0%

Net income-$92.5M+37.0%

EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%

Total debt$691.7M+334%

Total equity$491.4M+3.3%

Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%

CapEx$21.8M+73.0%

Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%

Enterprise value$12.77B+175%

P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp

Operating margin-33.3%-11.0pp

Net margin-30.9%-10.5pp

FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp

Debt / equity1.4×+1.1×

Current ratio4.1×-5.6×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:Revenues.

The official record: Ionis Pharmaceuticals’s 10-K, filed February 26, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's revenue?: Ionis Pharmaceuticals (IONS) reported revenue of $203.33M in Q4 2025.
What does revenue mean?: The total amount of money brought in by the company from its business activities.
How do you interpret revenue?: An increase indicates successful commercialization, pipeline execution, or growth in partnership-based revenue streams.
How does revenue compare across companies?: The most fundamental metric for comparing the scale and growth trajectory of companies within the same industry.