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Septerna, Inc. SEPN Material Right — Non Refundable One Time Upfront Payment Received

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Other financials

Income statement

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Revenue$26.5M+12,011%
Operating income-$13.3M+48.7%
Net income-$8.6M+59.8%
EPS (diluted)-$0.19+61.2%

Balance sheet

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Cash & equivalents$71.6M-65.9%
Total debt$23.1M-7.7%
Total equity$378.5M+195%
Total assets$569.7M+31.3%

Cash flow

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Operating cash flow-$25.6M-9.8%
CapEx$832.0K+118%
Free cash flow-$26.5M-11.5%

Valuation

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Market cap$1.62B+319%
Enterprise value$1.58B+1,325%
P/S22.5×-374×

Profitability

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Operating margin-77.1%-38.4pp
Net margin-49.9%-24.9pp
FCF margin467.9%+243pp

Returns & leverage

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Return on equity-12.2%
Debt / equity0.1×
Current ratio4.7×-27.5×

Where this comes from

Reported directly by Septerna, Inc. in its filing.

Tagged under the XBRL concept sepn:NonRefundableOneTimeUpfrontPaymentReceived.

The official record: Septerna, Inc.’s 10-Q, filed May 11, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Septerna, Inc.'s material right — non refundable one time upfront payment received?
Septerna, Inc. (SEPN) reported material right — non refundable one time upfront payment received of $41.2M in Q1 2026.
How has Septerna, Inc.'s material right — non refundable one time upfront payment received changed year-over-year?
Septerna, Inc.'s material right — non refundable one time upfront payment received increased by 300.0% year-over-year, from $10.3M to $41.2M.
What does material right — non refundable one time upfront payment received mean?
This metric tracks the initial cash consideration received upon the execution of a contract that is not subject to refund, regardless of future performance outcomes. It provides immediate liquidity and serves as a key indicator of the initial commercial validation of a company's technology or drug pipeline. Monitoring this inflow helps investors assess the company's ability to monetize its intellectual property early in the partnership lifecycle.