What is Septerna, Inc.'s change in lease liabilities?

Septerna, Inc. (SEPN) reported change in lease liabilities of -$535K in Q1 2026.

How has Septerna, Inc.'s change in lease liabilities changed year-over-year?

Septerna, Inc.'s change in lease liabilities decreased by 18.9% year-over-year, from -$450K to -$535K.

What does change in lease liabilities mean?

Cash payments for operating leases reducing the lease liability, partially offset by new lease commencements.

Septerna, Inc. SEPN Change in Lease Liabilities

Change in Lease Liabilities at other companies

Nurix Therapeutics, Inc.NRIX

$205K+112%

PrecigenPGEN

-$75K+21.1%

Catalyst PharmaceuticalCPRX

-$106K-9.3%

Apogee Therapeutics, Inc.APGE

-$802K+20.9%

Arrowhead ResearchARWR

-$1.21M-7.5%

Enliven TherapeuticsELVN

-$97K-40.6%

Other financials

Income statement

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Revenue$26.5M+12,011%

Operating income-$13.3M+48.7%

Net income-$8.6M+59.8%

EPS (diluted)-$0.19+61.2%

Balance sheet

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Cash & equivalents$71.6M-65.9%

Total debt$23.1M-7.7%

Total equity$378.5M+195%

Total assets$569.7M+31.3%

Cash flow

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Operating cash flow-$25.6M-9.8%

CapEx$832.0K+118%

Free cash flow-$26.5M-11.5%

Valuation

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Market cap$1.62B+319%

Profitability

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Operating margin-77.1%-38.4pp

Net margin-49.9%-24.9pp

FCF margin467.9%+243pp

Returns & leverage

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Return on equity-12.2%—

Debt / equity0.1×—

Current ratio4.7×-27.5×

Where this comes from

Reported directly by Septerna, Inc. in its filing.

Tagged under the XBRL concept us-gaap:IncreaseDecreaseInOperatingLeaseLiability.

The official record: Septerna, Inc.’s 10-Q, filed May 11, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Septerna, Inc.'s change in lease liabilities?: Septerna, Inc. (SEPN) reported change in lease liabilities of -$535K in Q1 2026.
How has Septerna, Inc.'s change in lease liabilities changed year-over-year?: Septerna, Inc.'s change in lease liabilities decreased by 18.9% year-over-year, from -$450K to -$535K.
What does change in lease liabilities mean?: Cash payments for operating leases reducing the lease liability, partially offset by new lease commencements.