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Septerna, Inc. SEPN Invested capital

Discontinued — last reported Q1 '26

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Other financials

Income statement

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Revenue$26.5M+12,011%
Operating income-$13.3M+48.7%
Net income-$8.6M+59.8%
EPS (diluted)-$0.19+61.2%

Balance sheet

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Cash & equivalents$71.6M-65.9%
Total debt$23.1M-7.7%
Total equity$378.5M+195%
Total assets$569.7M+31.3%

Cash flow

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Operating cash flow-$25.6M-9.8%
CapEx$832.0K+118%
Free cash flow-$26.5M-11.5%

Valuation

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Market cap$1.62B+319%

Profitability

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Operating margin-77.1%-38.4pp
Net margin-49.9%-24.9pp
FCF margin467.9%+243pp

Returns & leverage

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Return on equity-12.2%
Debt / equity0.1×
Current ratio4.7×-27.5×

Where this comes from

Calculated from Septerna, Inc.’s reported figures.

The official record: Septerna, Inc.’s 10-Q, filed May 11, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Septerna, Inc.'s invested capital?
Septerna, Inc. (SEPN) reported invested capital of $329.94M in Q1 2026.
How has Septerna, Inc.'s invested capital changed year-over-year?
Septerna, Inc.'s invested capital increased by 156.4% year-over-year, from -$585.29M to $329.94M.
What is the long-term trend for Septerna, Inc.'s invested capital?
Over 2 years (2023 to 2025), Septerna, Inc.'s invested capital has grown at a 57.9% compound annual growth rate (CAGR), from -$114.29M to $284.83M.
What does invested capital mean?
Total debt plus shareholders' equity minus cash, at the quarter end. The capital actually put to work in the operating business — the denominator of return on invested capital (ROIC).