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Septerna, Inc. SEPN Unrealized gains (losses) on available-for-sale securities

Unrealized gains (losses) on available-for-sale securities at other companies

Arrowhead Research logo
Arrowhead ResearchARWR
-$6.93M-1,162%
Enliven Therapeutics logo
Enliven TherapeuticsELVN
-$716K-908%
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Scholar RockSRRK
-$71K-129%
Rhythm Pharmaceuticals, Inc. logo
Rhythm Pharmaceuticals, Inc.RYTM
-$544K-5,340%

Other financials

Income statement

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Revenue$26.5M+12,011%
Operating income-$13.3M+48.7%
Net income-$8.6M+59.8%
EPS (diluted)-$0.19+61.2%

Balance sheet

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Cash & equivalents$71.6M-65.9%
Total debt$23.1M-7.7%
Total equity$378.5M+195%
Total assets$569.7M+31.3%

Cash flow

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Operating cash flow-$25.6M-9.8%
CapEx$832.0K+118%
Free cash flow-$26.5M-11.5%

Valuation

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Market cap$1.62B+319%

Profitability

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Operating margin-77.1%-38.4pp
Net margin-49.9%-24.9pp
FCF margin467.9%+243pp

Returns & leverage

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Return on equity-12.2%
Debt / equity0.1×
Current ratio4.7×-27.5×

Where this comes from

Reported directly by Septerna, Inc. in its filing.

Tagged under the XBRL concept us-gaap:OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax.

The official record: Septerna, Inc.’s 10-Q, filed May 11, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Septerna, Inc.'s unrealized gains (losses) on available-for-sale securities?
Septerna, Inc. (SEPN) reported unrealized gains (losses) on available-for-sale securities of -$1.19M in Q1 2026.
How has Septerna, Inc.'s unrealized gains (losses) on available-for-sale securities changed year-over-year?
Septerna, Inc.'s unrealized gains (losses) on available-for-sale securities decreased by 935.2% year-over-year, from $142K to -$1.19M.
What does unrealized gains (losses) on available-for-sale securities mean?
This metric represents the change in the fair value of available-for-sale investment securities that has not yet been realized through a sale. It captures market-driven fluctuations in the value of a company's investment portfolio that are recorded in equity rather than the income statement. Monitoring this helps investors assess the volatility and unrealized performance of a company's treasury or investment assets.