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Spyre Therapeutics, Inc. SYRE Cash, Cash Equivalents, and Marketable Securities

Cash, Cash Equivalents, and Marketable Securities at other companies

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Other financials

Income statement

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Revenue-
Operating income-$45.6M+14.8%
Net income-$69.0M-54.1%
EPS (diluted)-$0.74-23.3%

Balance sheet

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Cash & equivalents$97.2M+100%
Total debt$4.3M-9.6%
Total equity$670.8M+39.0%
Total assets$764.0M+34.1%

Cash flow

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Operating cash flow-$57.4M-40.0%
CapEx-
Free cash flow-$39.4M-26.8%

Valuation

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Market cap$7.67B+307%

Profitability

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Operating margin-39,428.9%-49,795pp
Net margin-52,939.7%-61,871pp
FCF margin-3,442.8%-3,807pp

Returns & leverage

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Return on equity-31.1%-10.7pp
Debt / equity0.1×+0.1×
Current ratio+0.9×

Where this comes from

Reported directly by Spyre Therapeutics, Inc. in its filing.

Tagged under the XBRL concept us-gaap:DebtSecuritiesAvailableForSaleUnrealizedLossPosition.

The official record: Spyre Therapeutics, Inc.’s 10-Q, filed May 5, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Spyre Therapeutics, Inc.'s cash, cash equivalents, and marketable securities?
Spyre Therapeutics, Inc. (SYRE) reported cash, cash equivalents, and marketable securities of $432M in Q1 2026.
How has Spyre Therapeutics, Inc.'s cash, cash equivalents, and marketable securities changed year-over-year?
Spyre Therapeutics, Inc.'s cash, cash equivalents, and marketable securities increased by 310.8% year-over-year, from $105.15M to $432M.
What is the long-term trend for Spyre Therapeutics, Inc.'s cash, cash equivalents, and marketable securities?
Over 3 years (2022 to 2025), Spyre Therapeutics, Inc.'s cash, cash equivalents, and marketable securities has grown at a 93.0% compound annual growth rate (CAGR), from $25.17M to $180.96M.
What does cash, cash equivalents, and marketable securities mean?
This represents the most liquid assets held by the company, including cash on hand, bank deposits, and short-term investments that can be readily converted into cash. It serves as the primary buffer for operational liquidity and potential capital allocation activities. Investors monitor this to assess the company's ability to meet short-term obligations and fund growth initiatives.