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Spyre Therapeutics, Inc. SYRE Cash, Cash Equivalents, and Marketable Securities

Cash, Cash Equivalents, and Marketable Securities at other companies

Merck & Co. logo
Merck & Co.MRK
$292M-58.7%

Other financials

Income statement

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Revenue-
Operating income-$45.6M+14.8%
Net income-$69.0M-54.1%
EPS (diluted)-$0.74-23.3%

Balance sheet

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Cash & equivalents$97.2M+100%
Total debt$4.3M-9.6%
Total equity$670.8M+39.0%
Total assets$764.0M+34.1%

Cash flow

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Operating cash flow-$57.4M-40.0%
CapEx-
Free cash flow-$39.4M-26.8%

Valuation

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Market cap$9.25B+904%

Profitability

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Operating margin-39,428.9%-49,795pp
Net margin-52,939.7%-61,871pp
FCF margin-3,442.8%-3,807pp

Returns & leverage

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Return on equity-31.1%-10.7pp
Debt / equity0.1×+0.1×
Current ratio+0.9×

Where this comes from

Reported directly by Spyre Therapeutics, Inc. in its filing.

Tagged under the XBRL concept us-gaap:DebtSecuritiesAvailableForSaleUnrealizedLossPosition.

The source filing: Spyre Therapeutics, Inc.’s 10-Q, filed May 5, 2026.

Filed
May 5, 2026, 8:00 AM EDT
Fiscal quarter
Q1 FY2026
Calendar quarter
Q1 2026
Accession
0001636282-26-000050
Corporate bonds$$74,746$$(149)$$$$74,746$$(149)
U.S. government treasury securities95,038(296)95,038(296)
U.S. government agency securities122,231(382)122,231(382)
Total marketable securities$$431,995$$(1,057)$$$$431,995$$(1,057)
December 31, 2025
Less Than 12 Months12 Months or LongerTotal
Fair ValueUnrealizedLossesFair ValueUnrealizedLossesFair ValueUnrealizedLosses
Commercial paper$$99,837$$(80)$$$$99,837$$(80)

Item 1. Financial Statements (Unaudited).

FAQ

What is Spyre Therapeutics, Inc.'s cash, cash equivalents, and marketable securities?
Spyre Therapeutics, Inc. (SYRE) reported cash, cash equivalents, and marketable securities of $432M in Q1 2026.
How has Spyre Therapeutics, Inc.'s cash, cash equivalents, and marketable securities changed year-over-year?
Spyre Therapeutics, Inc.'s cash, cash equivalents, and marketable securities increased by 310.8% year-over-year, from $105.15M to $432M.
What is the long-term trend for Spyre Therapeutics, Inc.'s cash, cash equivalents, and marketable securities?
Over 3 years (2022 to 2025), Spyre Therapeutics, Inc.'s cash, cash equivalents, and marketable securities has grown at a 93.0% compound annual growth rate (CAGR), from $25.17M to $180.96M.
What does cash, cash equivalents, and marketable securities mean?
This represents the most liquid assets held by the company, including cash on hand, bank deposits, and short-term investments that can be readily converted into cash. It serves as the primary buffer for operational liquidity and potential capital allocation activities. Investors monitor this to assess the company's ability to meet short-term obligations and fund growth initiatives.

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