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Spyre Therapeutics, Inc. SYRE Investing Cash Flow

Investing Cash Flow at other companies

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Other financials

Income statement

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Revenue-
Operating income-$45.6M+14.8%
Net income-$69.0M-54.1%
EPS (diluted)-$0.74-23.3%

Balance sheet

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Cash & equivalents$97.2M+100%
Total debt$4.3M-9.6%
Total equity$670.8M+39.0%
Total assets$764.0M+34.1%

Cash flow

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Operating cash flow-$57.4M-40.0%
CapEx-
Free cash flow-$39.4M-26.8%

Valuation

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Market cap$9.12B+846%

Profitability

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Operating margin-39,428.9%-49,795pp
Net margin-52,939.7%-61,871pp
FCF margin-3,442.8%-3,807pp

Returns & leverage

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Return on equity-31.1%-10.7pp
Debt / equity0.1×+0.1×
Current ratio+0.9×

Where this comes from

Reported directly by Spyre Therapeutics, Inc. in its filing.

Tagged under the XBRL concept us-gaap:NetCashProvidedByUsedInInvestingActivities.

The source filing: Spyre Therapeutics, Inc.’s 10-Q, filed May 5, 2026.

Filed
May 5, 2026, 8:00 AM EDT
Fiscal quarter
Q1 FY2026
Calendar quarter
Q1 2026
Accession
0001636282-26-000050
Line itemThree Months Ended March 31, 2026Three Months Ended March 31, 2025
Proceeds from maturities and sales of marketable securities107,74871,383
Purchases of marketable securities(81,167)(71,444)
Proceeds from sale of in-process research and development asset30,000
Net cash provided by (used in) investing activities56,581(61)
CASH FLOWS FROM FINANCING ACTIVITIES
Proceeds from issuance of common stock in connection with at-the-market offering program, net of issuance costs9,750
Payment of deferred offering costs in connection with shelf registration(171)(93)
Proceeds from employee stock option exercises and employee stock plan purchases2,676218

Item 1. Financial Statements (Unaudited).

FAQ

What is Spyre Therapeutics, Inc.'s investing cash flow?
Spyre Therapeutics, Inc. (SYRE) reported investing cash flow of $56.58M in Q1 2026.
How has Spyre Therapeutics, Inc.'s investing cash flow changed year-over-year?
Spyre Therapeutics, Inc.'s investing cash flow increased by 92855.7% year-over-year, from -$61K to $56.58M.
What is the long-term trend for Spyre Therapeutics, Inc.'s investing cash flow?
Over 2 years (2022 to 2025), Spyre Therapeutics, Inc.'s investing cash flow has grown at a 58.6% compound annual growth rate (CAGR), from $57.01M to -$143.48M.
What does investing cash flow mean?
Total net cash provided by or used in investing activities — capex, acquisitions, investment purchases/sales, and other investing items.

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